New combo shows promise for Tough-to-Treat blood cancers
NCT ID NCT01869114
First seen Jan 11, 2026 · Last updated Jun 12, 2026 · Updated 26 times
Summary
This study tested a combination of two drugs, azacitidine and sirolimus, in 57 adults with high-risk myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) that came back or didn't respond to standard treatment. The goal was to see if the combination could improve blood cell counts or lead to remission. The approach aims to control the disease rather than cure it, as ongoing management is typically needed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Abington Hospital - Jefferson Health
Abington, Pennsylvania, 19001, United States
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Jefferson Health NJ Division (Kennedy Hospital)
Sewell, New Jersey, 08012, United States
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Jefferson Health, Aria Hospital
Philadelphia, Pennsylvania, 19124, United States
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Jefferson Health, Methodist Hospital
Philadelphia, Pennsylvania, 19148, United States
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Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, 19107, United States
Conditions
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