New hope for rare ovarian cancer: drug combo tested in japanese patients

NCT ID NCT06682572

First seen Jan 06, 2026 · Last updated Jun 14, 2026 · Updated 19 times

Summary

This study tests two drugs, avutometinib and defactinib, in 16 Japanese patients whose low-grade serous ovarian cancer has come back after platinum-based chemotherapy. The goal is to see if the combination can shrink tumors and control the disease. Participants must have measurable tumors and adequate organ function.

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Contacts and locations

Locations

  • Aichi Cancer Center Hospital

    Nagoya, Aichi-ken, 464-8681, Japan

  • Jikei University Hospital

    Minato, Tokyo, 105-0003, Japan

  • Kurume University Hospital

    Kurume, Fukuoka, 830-0011, Japan

  • Mie University Hospital

    Tsu, Mie-ken, 514-8507, Japan

  • Tohoku University Hospital

    Sendai, Miyagi, 980-8574, Japan

Conditions

Explore the condition pages connected to this study.