New combo therapy aims to boost platelets in immune disorder

NCT ID NCT07278908

First seen Jan 10, 2026 · Last updated May 12, 2026 · Updated 15 times

Summary

This study tests whether adding all-trans retinoic acid to avatrombopag works better than avatrombopag alone for adults with immune thrombocytopenia (ITP) who didn't improve with first treatment. About 248 participants will take the drugs for up to 24 weeks, then taper off, and be followed for a year. The goal is to see if more people can stop treatment and maintain safe platelet levels.

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