Year-Long autism drug safety trial seeks to tame irritability

NCT ID NCT05555615

Summary

This study aimed to check the long-term safety and side effects of a medication called pimavanserin for children and teens with autism who experience significant irritability. It was a one-year follow-up for 209 participants aged 5 to 17 who had completed a prior shorter trial. The main goal was to see how well patients tolerated the medication over a longer period, while also tracking changes in their irritability and overall improvement.

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Contacts and locations

Locations

  • 1st Allergy and Clinical Research Group, d/b/a IMUNOe Research Centers

    Centennial, Colorado, 80112, United States

  • AIM Trials, LLC

    Plano, Texas, 75093, United States

  • AMR Baber Research Incorporated

    Naperville, Illinois, 60563, United States

  • APG Research, LLC

    Orlando, Florida, 32803-3809, United States

  • Azienda Ospedaliera Universitaria "Federico II"

    Naples, 80131, Italy

  • Azienda Ospedaliera Universitaria Integrata di Verona (AOUI)

    Verona, 37126, Italy

  • Békés Megyei Központi Kórház

    Gyula, H-5700, Hungary

  • CHU de Nantes

    Nantes, 44093, France

  • Centre Hospitalier Charles Perrens

    Bordeaux, 33076, France

  • Centre de Ressources Autisme Rhône-Alpes - Center Hospitalier le Vinatier

    Bron, 69678, France

  • Centrum Badań Klinicznych PI-House Sp. z o.o.

    Gdansk, 80-546, Poland

  • Centrum Neuropsychiatrii Neuromed SP ZOZ

    Wroclaw, 54-238, Poland

  • Children's Health Queensland Hospital and Health Service

    South Brisbane, Queensland, 4101, Australia

  • Children's Research Institute

    Washington D.C., District of Columbia, 20010, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Clinical Center of Vojvodina, Clinic for Psychiatry

    Novi Sad, 21000, Serbia

  • Clinical Research of Southern Nevada, LLC

    Las Vegas, Nevada, 89128, United States

  • Cortica Inc.

    San Rafael, California, 94903, United States

  • Cortica Inc. (Glendale)

    Glendale, California, 91361, United States

  • ERG Clinical Research - New York, PLLC DBA Richmond Behavioral Associates

    Staten Island, New York, 10314, United States

  • Eastside Therapeutic Resource, Inc. dba Core Clinical Research

    Everett, Washington, 98201, United States

  • Fondazione Istituto Neurologico Nazionale Casimiro Mondino - IRCCS

    Pavia, 27100, Italy

  • Fondazione PTV - Policlinico Tor Vergata

    Rome, 00133, Italy

  • Gdańskie Centrum Zdrowia Sp. z o.o.

    Gdansk, 80-542, Poland

  • Ginemedica Sp. Zoo, S. K.

    Wroclaw, 50-414, Poland

  • Hospital Clínic de Barcelona

    Barcelona, 08036, Spain

  • Hospital General de Alicante

    Alicante, 03010, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Institut Global d´Atenció Integral del Neurodesenvolupament (IGAIN)

    Barcelona, 08007, Spain

  • Institute of Mental Health

    Belgrade, 11000, Serbia

  • L'Assistance Publique - Hôpitaux de Paris, labélisé Institut Carnot

    Paris, 75019, France

  • La Nostra Famiglia - Scientifica IRCCS Eugenio Medea

    Bosisio Parini, LC, 23842, Italy

  • Magyarországi Református Egyház Bethesda Gyermekkórháza

    Budapest, H-1146, Hungary

  • MedicMental Indywidualna Specjalistyczna Praktyka Lekarska Monika Szewczuk-Boguslawska

    Wroclaw, 54-617, Poland

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Monash Health

    Clayton, Victoria, 3168, Australia

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

  • NAVICULA - Centrum Diagnozy i Terapii Autyzmu

    Lodz, 91-129, Poland

  • Policlinico Riuniti - Azienda Ospedaliero Universitaria

    Foggia, 71122, Italy

  • Quest Therapeutics of Avon Lake dba Haidar Almhana Nieding LLC

    Avon Lake, Ohio, 44012, United States

  • Red Oak Psychiatry Associates, PA

    Houston, Texas, 77090, United States

  • Relaro Medical Trials, LLC

    Dallas, Texas, 75243, United States

  • Southwest Autism Research and Resource Center

    Phoenix, Arizona, 85006, United States

  • Szegedi Tudományegyetem

    Szeged, H-6725, Hungary

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19146, United States

  • The EHS Medical Practice, PA, D/B/A Sarkis Clinical Trials

    Gainesville, Florida, 32607, United States

  • University Clinical Center Kragujevac, Clinic for Psychiatry

    Kragujevac, 34000, Serbia

  • University Clinical Center Nis, Center for Mental Health

    Niš, 18000, Serbia

Conditions

Explore the condition pages connected to this study.