New test could help IVF patients pick the best embryo without invasive biopsy

NCT ID NCT07359703

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new test called the Aurora test, which uses cells that normally surround the egg (cumulus cells) to help select the best embryo for transfer in IVF. The test is non-invasive and aims to improve pregnancy and live birth rates compared to the standard method of judging embryos by appearance alone. About 1,028 women undergoing ICSI will participate, and the study will compare embryo selection based on morphology versus morphology plus the Aurora test.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Aurora test (non-invasive genetic analysis of cumulus cells)
What this could lead to
If successful, this test could provide a more objective way to choose the embryo with the highest chance of pregnancy, potentially improving IVF success rates without invasive procedures.
What could go wrong
This is an early-stage study comparing the test to standard methods, and it may not show a significant improvement. The test is also specific to certain stimulation protocols, so results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ghent University Hospital

    RECRUITING

    Ghent, Belgium

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