Cancer drug combo trial halted early: what we know

NCT ID NCT04972110

First seen Nov 01, 2025 · Last updated May 18, 2026 · Updated 30 times

Summary

This study tested a combination of two drugs (RP-3500 and either niraparib or olaparib) in 156 adults with advanced solid tumors that had not responded to standard treatments. The goal was to find safe doses and see if the combo could shrink tumors. The trial was terminated early, so final results are not available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Participating Site # 1001

    Houston, Texas, 77030, United States

  • Participating Site # 1008

    New York, New York, 10032, United States

  • Participating Site # 1013

    Salt Lake City, Utah, 84112, United States

  • Participating Site # 1016

    Rochester, Minnesota, 55905, United States

  • Participating Site #1009

    Baltimore, Maryland, 21205, United States

  • Participating Site #1012

    New Haven, Connecticut, 06511, United States

  • Participating Site #1015

    Ann Arbor, Michigan, 48109, United States

  • Participating Site #1017

    Jacksonville, Florida, 32224, United States

  • Participating Site #1018

    Phoenix, Arizona, 97401, United States

  • Participating Site #1025

    San Francisco, California, 94158, United States

  • Participating Site #1026

    New York, New York, 10029, United States

  • Participating Site #1028

    Aurora, Colorado, 80012, United States

  • Participating Site #1029

    Eugene, Oregon, 97401, United States

Conditions

Explore the condition pages connected to this study.