Could a few drops under the tongue replace a needle? atropine study explores

NCT ID NCT06366087

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether atropine eye drops placed under the tongue enter the bloodstream as effectively as a standard injection. Forty-six healthy adults each received both forms in random order. Researchers measured drug levels in blood samples over eight hours to see if the two methods are bioequivalent.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

atropine sulfate

What this could lead to

If successful, this could show that giving atropine under the tongue is a safe and effective alternative to injections, which could be useful in emergencies.

What could go wrong

This is a small, early-phase study in healthy volunteers, not patients. It only measures drug levels in the blood, not actual treatment effects, so real-world benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johnson County Clin-Trials (JCCT)

    Lenexa, Kansas, 66219, United States