Can a daily eye drop stop Kids' eyesight from worsening?
NCT ID NCT07028827
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 study tests whether low-dose atropine eye drops (0.025% and 0.05%) can slow the progression of myopia (nearsightedness) in children and teens aged 3 to 17. About 234 participants across Europe will use the drops once nightly for 2 years. The goal is to see if these drops can keep eyesight from getting worse, reducing the need for stronger glasses later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
atropine eye drops (0.025% and 0.05%)
What this could lead to
If successful, this could provide a safe, effective daily eye drop to slow or stop nearsightedness from getting worse in children and teens.
What could go wrong
This is a phase 3 trial, but results may vary by child. Atropine can cause side effects like light sensitivity or blurry near vision. Long-term benefits beyond 2 years are not yet known.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda Ospedale Università Padova
NOT_YET_RECRUITINGPadua, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Children's Memorial Health Institute, Department of Ophthalmology
RECRUITINGWarsaw, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital Puerta del Mar (INIBICA)
RECRUITINGCadiz, 11009, Spain
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario La Paz
RECRUITINGMadrid, 28046, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Parc Taulí
RECRUITINGBarcelona, 08208, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Northern Ireland Clinical Research Facility. U Floor. Belfast City Hospital
RECRUITINGBelfast, BT9 7AB, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ophthalmology - AOU Consorziale Policlinico - Ospedale Pediatrico Giovanni XXIII
RECRUITINGBari, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pediatric Ophthalmology - Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico Milan
RECRUITINGMilan, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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R&D, Moorfields Eye Hospital
RECRUITINGLondon, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Email: •••••@•••••
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School of Optometry, Aston University
RECRUITINGBirmingham, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Centre Mother Teresa (UHCT), Paediatric Department
RECRUITINGTirana, Albania
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact