Hope for muscle stiffness: new drug shows promise in Long-Term trial

NCT ID NCT06549400

ENROLLING_BY_INVITATION Symptom relief Sponsor: Lupin Ltd. Source: ClinicalTrials.gov ↗

First seen Jan 26, 2026 · Last updated May 15, 2026 · Updated 14 times

Summary

This study looks at the long-term safety and effectiveness of a daily medication called mexiletine PR for reducing muscle stiffness (myotonia) in people with myotonic dystrophy types 1 and 2. It is for those who have already completed a previous study of the same drug. The goal is to see if the drug continues to work well and remains safe over 26 weeks.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, Denmark

  • Azienda Ospedaliera Universitaria Policlinico Tor Vergata

    Rome, Italy

  • Laboratory for Muscle Diseases and Neuropathies

    Leuven, Belgium

  • Ludug-Maximilians University

    München, Germany

  • University College Hospital

    London, United Kingdom

  • University Hospital of Madrid

    Madrid, Spain

Conditions

Explore the condition pages connected to this study.