New hope for frail lung cancer patients: immunotherapy combo shows promise

NCT ID NCT04221529

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 25 times

Summary

This study tested a combination of the immunotherapy drug atezolizumab with standard chemotherapy in 70 patients with advanced small cell lung cancer who were in poor health (ECOG 2). The goal was to see if this treatment is safe and effective for this group, who often have very short survival times. The approach aims to improve overall survival and control the disease, though it is not a cure and ongoing management is needed.

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Contacts and locations

Locations

  • Asklepios Klinik Altona

    Hamburg, 22763, Germany

  • Brüderkrankenhaus St. Josef

    Paderborn, 33098, Germany

  • Fachkliniken Wangen

    Wangen, 88239, Germany

  • Helios Dr. Horst Schmidt Kliniken Wiesbaden

    Wiesbaden, 65199, Germany

  • Helios Universitätsklinikum

    Wuppertal, 42283, Germany

  • Johannes Wesling Klinikum

    Minden, 32429, Germany

  • Karl Landsteiner Institut für Lungenforschung und Pneumologische Onkologie c/o Wilhelminenspital der Stadt Wien

    Vienna, 1160, Austria

  • Klinikum Esslingen GmbH

    Esslingen am Neckar, 73730, Germany

  • Klinikum Klagenfurt

    Klagenfurt, 9020, Austria

  • Klinikum Löwenstein gGmbH

    Löwenstein, 74245, Germany

  • Klinikum der Universität München

    München, 80336, Germany

  • Krankenhaus Martha-Maria Halle-Dölau

    Halle, 06120, Germany

  • LungenClinic Grosshansdorf GmbH

    Großhansdorf, 22927, Germany

  • Niels-Stensen-Kliniken

    Georgsmarienhütte, 49124, Germany

  • St. Josef Hospital

    Bochum, 44791, Germany

  • Universität Heidelberg

    Heidelberg, 69126, Germany

  • Universitätsklinikum Freiburg

    Freiburg im Breisgau, 79106, Germany

  • Universitätsklinikum Gießen und Marburg GmbH

    Marburg, 35043, Germany

  • Universitätsklinikum Krems

    Krems, 3500, Austria

Conditions

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