New hope for rare blood disorder: drug aims to prevent clots during surgery and delivery

NCT ID NCT04918173

First seen Nov 21, 2025 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tests a drug called Atenativ in people with a rare inherited condition that raises their risk of dangerous blood clots. The goal is to see if the drug can prevent clots during surgery or childbirth. About 38 adults and teens will take part, and researchers will monitor for side effects and how well the drug works.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aversi Clinic

    RECRUITING

    Tbilisi, Georgia

  • Bleeding and Clotting Disorders Institute

    RECRUITING

    Peoria, Illinois, 61615, United States

  • Central University Hospital of Asturias

    RECRUITING

    Oviedo, Principality of Asturias, 33011, Spain

  • Centre Hospitalier Universitaire de Rouen (CHU de Rouen) - Centre de Traitement des Maladies Hemorragiques (CRTH) (Centre d'Hemophiles)

    RECRUITING

    Rouen, France

  • Centre de Référence de l'Hémophilie Unité d'Hémostase Clinique Hôpital Cardiologique Louis Pradel

    RECRUITING

    Bron, France

  • Centre for Thrombosis and Haemaostasis

    RECRUITING

    Nymburk, Czechia

  • Clinical Center of Serbia

    RECRUITING

    Belgrade, Serbia

  • Duke University

    RECRUITING

    Durham, North Carolina, 27708, United States

  • Emergency County Hospital Craiova

    RECRUITING

    Craiova, Romania

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, Italy

  • Georgetown University

    RECRUITING

    Washington D.C., District of Columbia, 20057, United States

  • Gerinnungszentrum Rhein-Ruhr

    RECRUITING

    Duisburg, Germany

  • Hospital Universitario La Paz

    RECRUITING

    Madrid, 28046, Spain

  • Hospital Universitario Morales Meseguer

    RECRUITING

    Murcia, Spain

  • Klinik fur Angiologie Hamostaseologie Haus 12 A Gerinnungssprechstunde

    RECRUITING

    Berlin, Germany

  • Ourense University Hospital

    RECRUITING

    Ourense, 32005, Spain

  • Rabin Medical Centre, Institute of Haematology

    RECRUITING

    Petah Tikva, Israel

  • Royal-free Hospital-Katherine Dormandy Haemophilia and Thrombosis Centre

    RECRUITING

    London, United Kingdom

  • Sheba Medical Centre

    RECRUITING

    Ramat Gan, Israel

  • St. Thomas Hospital

    RECRUITING

    London, United Kingdom

  • UKB Bonn Institut für Experimentelle Hämatologie und Transfusionsmedizin

    RECRUITING

    Bonn, Germany

  • Unita Strutturale Complessa di Immunoematologia e Medicina Trasfusionale -Dipartimento Interaziendale di Medicina Trasfusionale ed Ematologia - ASST Papa Giovanni XXIII ematologia Piazza OMS, 1

    RECRUITING

    Bergamo, 24127, Italy

  • Universita degli Studi di Milano - IRCCS Ospedale Maggiore Policlinico - Centro Emofilia e Trombosi Angelo Bianchi Bonomi

    RECRUITING

    Milan, Italy

  • University Hospital of Reims

    RECRUITING

    Reims, France

  • University of Debrecen, Medical and Health Science Centre

    RECRUITING

    Debrecen, Hungary

  • University of Miami

    RECRUITING

    Miami, Florida, 33124, United States

  • University of Padua Medical School

    RECRUITING

    Padua, Italy

  • Universitätsklinik für Innere Medizin Klinische Abteilung für Hämatologie und Hämostaseologie

    RECRUITING

    Vienna, Austria

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

  • Yeolyan Hematology and Oncology Centre

    NOT_YET_RECRUITING

    Yerevan, Armenia

Conditions

Explore the condition pages connected to this study.