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New hope for tough prostate cancer: drug combo trial opens

NCT ID NCT07002320

Recruiting now Disease control Sponsor: Institute of Cancer Research, United Kingdom Source: ClinicalTrials.gov ↗

First seen Jan 07, 2026 · Last updated May 01, 2026 · Updated 16 times

Summary

This study tests whether adding an experimental drug (SX-682) to a standard hormone therapy (apalutamide) can help men with a hard-to-treat type of advanced prostate cancer. About 78 men will take part to find the safest dose and see if the combination shrinks tumors or lowers PSA levels. The goal is to control the cancer, not cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Belfast Health and Social Care Trust

    RECRUITING

    Belfast, BT9 7AB, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cambridge University Hospitals NHS Foundation Trust

    RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oncology Institute of Southern Switzerland

    NOT_YET_RECRUITING

    Bellinzona, CH6500, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • The Royal Marsden NHS Foundation Trust - Drug Development Unit

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

METASTATIC CASTRATE RESISTANT PROSTATE CANCER (MCRPC)