Glow-in-the-Dark dye could prevent surgical accidents
NCT ID NCT05999747
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a dye called ASP5354 that makes the ureter glow under special cameras during abdominal surgery. The goal is to help surgeons avoid accidentally cutting or damaging the ureter, a rare but serious complication. 95 adults with normal or impaired kidney function received the dye, and surgeons compared visibility under normal light versus the glow mode. The trial is complete, and results will show if the dye improves ureter visibility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ASP5354 (a medical dye injected into the bloodstream to highlight the ureter during surgery)
What this could lead to
If successful, this dye could become a standard tool to help surgeons avoid accidentally injuring the ureter during abdominal surgeries.
What could go wrong
This is a completed phase 3 trial with only 95 participants, so results may not apply to all patients or surgeries. The dye's effectiveness depends on the imaging equipment and surgeon skill.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Benaroya Research Institute at VA Mason
Seattle, Washington, 98101, United States
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Cedars Sinai Medical Center
Los Angeles, California, 90048, United States
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Cleveland Clinic Florida
Weston, Florida, 33331, United States
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Duke University Hospital
Durham, North Carolina, 27705, United States
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Firsthealth of the Carolinas INC
Pinehurst, North Carolina, 28374, United States
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Hoag Memorial Hospital Presbyterian
Newport Beach, California, 92663, United States
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Temple University Hospital
Philadelphia, Pennsylvania, 19140, United States
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University of Nevada, Las Vegas
Las Vegas, Nevada, 89102, United States
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University of South Florida
Tampa, Florida, 33606, United States
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Washington University Center
St Louis, Missouri, 63110, United States