Glow-in-the-dark dye helps surgeons avoid a rare but serious injury

NCT ID NCT05999747

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 28 times

Summary

This study tested a new dye called ASP5354 that makes the ureter (the tube from kidney to bladder) glow under a special camera during abdominal surgery. 95 adults having abdominal surgery received the dye, and surgeons compared how well they could see the ureter with normal light versus the glowing dye. The goal was to see if the dye helps prevent accidental injury to the ureter.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Benaroya Research Institute at VA Mason

    Seattle, Washington, 98101, United States

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Cleveland Clinic Florida

    Weston, Florida, 33331, United States

  • Duke University Hospital

    Durham, North Carolina, 27705, United States

  • Firsthealth of the Carolinas INC

    Pinehurst, North Carolina, 28374, United States

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California, 92663, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Temple University Hospital

    Philadelphia, Pennsylvania, 19140, United States

  • University of Nevada, Las Vegas

    Las Vegas, Nevada, 89102, United States

  • University of South Florida

    Tampa, Florida, 33606, United States

  • Washington University Center

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.