New ultrasound dye could spot hidden heart defects
NCT ID NCT06938347
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This phase 3 trial tests a new contrast agent called ASI-02 against the standard agitated saline for detecting right-to-left shunts in the heart. About 300 adults with suspected shunts will receive both agents during an echocardiogram. The goal is to see if ASI-02 finds shunts more accurately and safely than the current method.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ASI-02 (a contrast agent for ultrasound)
What this could lead to
If successful, ASI-02 could become a more reliable and consistent contrast agent for detecting heart defects that allow blood to bypass the lungs.
What could go wrong
This is a phase 3 trial, but the primary goal is diagnostic accuracy, not treatment. Even if ASI-02 works better than saline, it may not change patient outcomes or be widely adopted.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CentraCare
RECRUITINGSaint Cloud, Minnesota, 56303, United States
Contact
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Jackson Heart Clinic
RECRUITINGJackson, Mississippi, 39216, United States
Contact
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact
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Toronto General
RECRUITINGToronto, M5G 2C4, Canada
Contact