New hope for leukemia patients after first treatment fails

NCT ID NCT05384587

Ongoing Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing a drug called asciminib for adults with chronic phase chronic myeloid leukemia (CML). It includes two groups: patients whose first treatment didn't work well or caused side effects, and newly diagnosed patients. The goal is to see if asciminib can effectively control the leukemia by reducing the amount of cancer-causing protein in the blood.

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Contacts and locations

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Locations

Alaska Oncology and Hematology

Anchorage, Alaska, 99508, United States
Alta Bates Summit Medical Center

Oakland, California, 94609, United States
Augusta University Georgia

Augusta, Georgia, 30912, United States
Avera Cancer

Sioux Falls, South Dakota, 57105, United States
Baptist MD Anderson Cancer Center

Jacksonville, Florida, 32207, United States
Bon Secours Cancer Center

Greenville, South Carolina, 29607, United States
Care Access Research

Easton, Pennsylvania, 18045, United States
Care Access Research Clifton

Clifton, New Jersey, 07013, United States
City Of Hope Atlanta

Atlanta, Georgia, 30033, United States
City of Hope National Medical

Duarte, California, 91010, United States
City of Hope Phoenix

Scottsdale, Arizona, 85258, United States
Clinical Research Alliance

Lake Success, New York, 11042, United States
Community Cancer Trials of Utah

Ogden, Utah, 84405, United States
Ctr For Cancer And Blood Disorders

Fort Worth, Texas, 76104, United States
Dana Farber Cancer Center

Boston, Massachusetts, 02215, United States
Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States
Dean Health System

Madison, Wisconsin, 53717, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Emory University School of Medicine Winship Cancer Institute

Atlanta, Georgia, 30308, United States
Florida Cancer Specialists

Fort Myers, Florida, 33901, United States
Florida Cancer Specialists East

Stuart, Florida, 34994, United States
Florida Cancer Specialists-North

St. Petersburg, Florida, 33705, United States
Franciscan Health Indianapolis

Indianapolis, Indiana, 42637, United States
Fred Hutch Cancer Research

Seattle, Washington, 98109, United States
Gabrail Cancer Center

Canton, Ohio, 44718, United States
Hackensack Meridian Health

Edison, New Jersey, 88837, United States
Hackensack University Medical Ctr

Hackensack, New Jersey, 07601, United States
Hematology Oncology Care

Cincinnati, Ohio, 45236, United States
Henry Ford Hospital

Detroit, Michigan, 48202-2689, United States
Holden Comp Can Cent Quad Cities U

Iowa City, Iowa, 52242, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
Huntsman Cancer Institute

Salt Lake City, Utah, 84112, United States
Investigative Clinicl Rsrch of Indi

Indianapolis, Indiana, 46260, United States
Jackson Onc Associates

Jackson, Mississippi, 39216, United States
James Cancer Hospital and Solove Research Institute Ohio State

Columbus, Ohio, 43210, United States
Louisiana State University

Shreveport, Louisiana, 71130, United States
Lundquist Inst BioMed at Harbor

Torrance, California, 90509-2910, United States
Manhattan Hematol Oncol Associates

New York, New York, 10016, United States
Mays Cancer Center

San Antonio, Texas, 78229, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Mt Sinai Medical Center

New York, New York, 10029-6574, United States
NYU Langone Long Island

Mineola, New York, 11501, United States
Nebraska Hematology Oncology P C

Lincoln, Nebraska, 68506, United States
New York Bld And Cancer Specialists

Port Jefferson, New York, 11776, United States
Northwest Georgia Oncology Center

Marietta, Georgia, 30060, United States
Northwest Medical Specialties

Tacoma, Washington, 98405, United States
Novant Health Heart Vas Inst

Charlotte, North Carolina, 28204, United States
Onco Inst of Hope and Innovation

Cerritos, California, 90703, United States
Oregon Health Sciences University

Portland, Oregon, 97239, United States
Rocky Mountain Cancer Centers

Boulder, Colorado, 80304, United States
Rutgers Cancer Institute of NJ

New Brunswick, New Jersey, 08901, United States
SUNY Stony Brook Medical Oncology

Stony Brook, New York, 11794-8174, United States
SUNY Upstate Medical Center

Syracuse, New York, 13210, United States
Sarah Cannon Research Institute

Nashville, Tennessee, 37203, United States
Siteman Cancer Center

St Louis, Missouri, 63110, United States
St Vincent Frontier Cancer Center

Billings, Montana, 59102, United States
Texas Oncology

Dallas, Texas, 75251, United States
Texas Oncology Northeast Texas

Tyler, Texas, 75702, United States
Texas Oncology P A

Austin, Texas, 78121, United States
Texas Oncology San Antonio

San Antonio, Texas, 78258, United States
The Stamford Hospital

Stamford, Connecticut, 06904, United States
Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States
UCLA

Los Angeles, California, 90095, United States
UCSF Fresno Internal Medicine

Fresno, California, 93701, United States
UNM

Albuquerque, New Mexico, 87102, United States
UPMC

Pittsburgh, Pennsylvania, 15213, United States
USO Arizona Oncology

Tucson, Arizona, 85711, United States
Univ of TX MD Anderson Cancer Cntr

Houston, Texas, 77030, United States
University Missouri Ellis Fischel Cancer Center

Columbia, Missouri, 65203, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35233-0271, United States
University of Kentucky

Lexington, Kentucky, 40536, United States
University of North Carolina

Chapel Hill, North Carolina, 27514, United States
VA Puget Sound Health Care System

Seattle, Washington, 98108, United States
Virginia Cancer Institute

Richmond, Virginia, 23230, United States
Virginia Cancer Specialists

Gainesville, Virginia, 20155, United States
Virginia K Crosson Cancer Center

Fullerton, California, 92835, United States
Virginia Oncology Associates

Norfolk, Virginia, 23502, United States
Wake Forest Uni Health Sci

Winston-Salem, North Carolina, 27157, United States
Wichita Community Clcl Onco Program

Wichita, Kansas, 67214, United States
Yale University School Of Medicine

New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.

CHRONIC MYELOGENOUS LEUKEMIA - CHRONIC PHASE