New drug combo aims to make kidney transplants safer and Longer-Lasting

NCT ID NCT05669001

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tested a new combination of drugs (siplizumab and belatacept) against standard care in 76 people who just received a kidney transplant. The goal was to see if the new combo is safer and helps the kidney work better. Participants took these medications for life to prevent organ rejection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist Medical Center

    Winston-Salem, North Carolina, 27157, United States

  • Emory University Hospital

    Atlanta, Georgia, 30322, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Inova Fairfax Hospital Medical Campus

    Falls Church, Virginia, 22042, United States

  • Loyola University Medical Center

    Maywood, Illinois, 60153, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ochsner Clinic Foundation

    New Orleans, Louisiana, 70121, United States

  • Tampa General Hospital

    Tampa, Florida, 33606, United States

  • University of California Davis Medical Center

    Sacramento, California, 95817, United States

  • University of California San Francisco Medical Center

    San Francisco, California, 94143, United States

  • University of Cincinnati Medical Center

    Cincinnati, Ohio, 45219, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Virginia Health

    Charlottesville, Virginia, 22903, United States

Conditions

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