Malaria drug could help fight dangerous virus in transplant patients
NCT ID NCT06853184
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding the malaria drug artesunate to standard antiviral treatment can better control cytomegalovirus (CMV) infection in people who have received a solid organ transplant (kidney, lung, heart, or liver). About 90 adult participants will receive either a low or high dose of artesunate plus standard care, or standard care alone. The goal is to see if the combination reduces the amount of virus in the blood more effectively than standard treatment alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
artesunate (an antimalarial drug) combined with ganciclovir or valganciclovir (standard antiviral drugs)
What this could lead to
If it works, this could offer a new combination treatment to better control CMV infections in transplant patients, potentially reducing complications.
What could go wrong
This is an early Phase 2 trial with only 90 participants, so results may not apply to everyone. The added benefit of artesunate is unproven, and side effects from the combination are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
Contact
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Princess Alexandra Hospital
TERMINATEDWoolloongabba, Australia
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Westmead Hospital
TERMINATEDWestmead, Australia