New drug tested for Ultra-Rare, dangerous cholesterol disorder

NCT ID NCT05217667

Summary

This study is testing an experimental drug called ARO-ANG3 for people with a rare, severe genetic condition that causes extremely high cholesterol from birth. The main goal is to see if the drug is safe and can effectively lower 'bad' cholesterol (LDL-C) over 24 weeks. Participants receive two doses and are monitored for 36 weeks, with an option to continue treatment for up to two more years.

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Contacts and locations

Locations

  • Research Site 1

    Québec, Quebec, G1V 4W2, Canada

  • Research Site 2

    Chicoutimi, Quebec, G7H 7K9, Canada

  • Research Site 3

    Nedlands, Western Australia, 6009, Australia

  • Research Site 4

    Mount Sinai, New York, 10029, United States

  • Research Site 5

    Cincinnati, Ohio, 45227, United States

  • Research Site 7

    Johannesburg, 2193, South Africa

  • Research Site 8

    Camperdown, New South Wales, 2050, Australia

Conditions

Explore the condition pages connected to this study.