New drug ARO-AAT shows promise in early safety trial for rare lung disease

NCT ID NCT03362242

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 26 times

Summary

This early-stage study tested the safety and how the body processes ARO-AAT in 45 healthy adults. The drug aims to lower abnormal protein levels that cause lung and liver damage in people with Alpha-1 Antitrypsin Deficiency. By focusing on safety first, this trial lays groundwork for future studies in patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site 1

    Grafton, Auckland, 1010, New Zealand

Conditions

Explore the condition pages connected to this study.