Hepatitis b drug trial halted: ARC-520 shows promise but study stopped early

NCT ID NCT02604212

Terminated Disease control Sponsor: Arrowhead Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jan 15, 2026 · Last updated May 24, 2026 · Updated 12 times

Summary

This study tested an experimental drug called ARC-520 in people with chronic hepatitis B who were already taking standard antiviral medications. The goal was to see if ARC-520 could lower hepatitis B surface antigen levels more than placebo. The trial was terminated early, so results are limited, but the approach aimed to better control the virus rather than cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Research Site 1

Hong Kong, 999077, China
Research Site 10

Leipzig, 04103, Germany
Research Site 11

Frankfurt, 60590, Germany
Research Site 12

Yangsan-si Gyeongnam, 626-770, South Korea
Research Site 13

Busan, 602-739, South Korea
Research Site 14

Seoul, 110-744, South Korea
Research Site 15

Incheon, 405-760, South Korea
Research Site 16

Seoul, 120-752, South Korea
Research Site 2

Hong Kong, China
Research Site 3

Tübingen, 72076, Germany
Research Site 4

Leipzig, 4103, Germany
Research Site 5

München, 81377, Germany
Research Site 6

Ulm, 89081, Germany
Research Site 7

Würzburg, 97080, Germany
Research Site 8

Hanover, 30625, Germany
Research Site 9

Hamburg, 20099, Germany

Conditions

Explore the condition pages connected to this study.

HEPATITIS B