Hepatitis b drug combo shows promise but study halted early

NCT ID NCT02738008

First seen Jan 15, 2026 · Last updated May 08, 2026 · Updated 15 times

Summary

This study looked at adding an experimental drug called ARC-520 to standard hepatitis B treatments (entecavir or tenofovir) in 12 people with chronic hepatitis B. Participants received 9 doses of ARC-520 over 36 weeks. The goal was to see if the combination could reduce a key virus marker (HBsAg) by at least 90%. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Research Site 1

    Hong Kong, 999077, China

  • Research Site 2

    Leipzig, 04103, Germany

  • Research Site 3

    Busan, 602-739, South Korea

  • Research Site 4

    Seoul, 110-744, South Korea

  • Research Site 5

    Incheon, 405-760, South Korea

  • Research Site 6

    Seoul, 120-752, South Korea

Conditions

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