Hepatitis b drug trial halted: ARC-520 shows promise but study ends early

NCT ID NCT02604199

Terminated Disease control Sponsor: Arrowhead Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jan 14, 2026 · Last updated May 12, 2026 · Updated 20 times

Summary

This study tested a new drug called ARC-520, given with standard antiviral pills, to see if it could lower hepatitis B virus levels in people with chronic infection. The trial included 58 adults who had been on antiviral treatment for at least 2 months. The study was stopped early, so results are limited.

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Contacts and locations

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Locations

Research Site 1

Hong Kong, 999077, China
Research Site 10

Leipzig, 04103, Germany
Research Site 11

Frankfurt, 60590, Germany
Research Site 12

Yangsan-si Gyeongnam, 626-770, South Korea
Research Site 13

Busan, 602-739, South Korea
Research Site 14

Seoul, 110-744, South Korea
Research Site 15

Incheon, 405-760, South Korea
Research Site 16

Seoul, 120-752, South Korea
Research Site 2

Hong Kong, China
Research Site 3

Tübingen, 72076, Germany
Research Site 4

Leipzig, 4103, Germany
Research Site 5

München, 81377, Germany
Research Site 6

Ulm, 89081, Germany
Research Site 7

Würzburg, 97080, Germany
Research Site 8

Hanover, 30625, Germany
Research Site 9

Hamburg, 20099, Germany

Conditions

Explore the condition pages connected to this study.

HEPATITIS B