Can a single dose predict autism treatment success?
NCT ID NCT07655115
First seen Jun 18, 2026 · Last updated Jun 23, 2026 · Updated 1 time
Summary
This study tests whether the drug arbaclofen can improve social function, anxiety, and quality of life in children and adolescents with autism. Participants first receive a single dose of arbaclofen or placebo to see if brain-wave changes can predict who will benefit. Then everyone gets arbaclofen for 10 weeks to measure real-world effects. The trial involves 103 participants aged 5–17 who have already taken part in a related study.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Assistance Publique Hopitaux De Paris
RECRUITINGParis, 75019, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Complejo Asistencial De Zamora Hospital Provincial De Zamora
RECRUITINGZamora, 49020, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital Clinic De Barcelona
RECRUITINGBarcelona, 08036, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital General Universitario Gregorio Marañón
RECRUITINGMadrid, 28007, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hospital Universitario De Salamanca
RECRUITINGSalamanca, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
arbaclofen
What this could lead to
If it works, this could point toward a treatment that eases social anxiety and improves quality of life for some children with autism.
What could go wrong
This is still an early-stage test of how well a single dose predicts longer-term response. The main trial is small (103 participants) and may not show clear benefits for everyone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.