New hope for FSGS: experimental drug APL2 enters Late-Stage trial

NCT ID NCT07213960

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called APL2 for people with a kidney disease called FSGS. The goal is to see if APL2 can reduce protein in the urine, a sign of kidney damage. The trial has two parts: first, adults will receive APL2 openly; then, both adults and adolescents will be randomly assigned to receive either APL2 or a placebo. About 270 participants will take part.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigator Site 1

    Chicago, Illinois, 60643, United States

  • Investigator Site 2

    New York, New York, 10032, United States

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Other studies related to the condition(s) this trial covers.