New hope for FSGS: experimental drug APL2 enters Late-Stage trial

NCT ID NCT07213960

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests an experimental drug called APL2 for people with a kidney disease called FSGS. The goal is to see if APL2 can reduce protein in the urine, a sign of kidney damage. The trial has two parts: first, adults will receive APL2 openly; then, both adults and adolescents will be randomly assigned to receive either APL2 or a placebo. About 270 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

focal segmental glomerulosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Investigator Site 1

    Chicago, Illinois, 60643, United States

  • Investigator Site 2

    New York, New York, 10032, United States