New hope for tough blood cancers? early trial launches
NCT ID NCT06372717
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study tests an experimental drug called APL-4098, alone or with standard treatments, in adults with acute myeloid leukemia (AML) or related blood disorders. The goal is to find a safe dose and see if it shrinks cancer. About 100 people will take part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
APL-4098 (an experimental oral drug)
What this could lead to
If successful, this could lead to a new treatment option for people with hard-to-treat AML or MDS.
What could go wrong
This is a very early Phase 1 trial with only 100 participants, so the drug may not prove effective or safe. Side effects are unknown and could be serious.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beatson West of Scotland Cancer Centre
RECRUITINGGlasgow, G120YN, United Kingdom
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Hollywood Private Hospital
ACTIVE_NOT_RECRUITINGNedlands, Western Australia, 6009, Australia
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Monash Health
RECRUITINGClayton, Victoria, 3168, Australia
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Royal Perth Hospital
RECRUITINGPerth, Western Australia, 6000, Australia
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Sarah Cannon Research Institute UK
RECRUITINGLondon, W1G 0PU, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Vincent's Hospital Melbourne
RECRUITINGFitzroy, Victoria, 3065, Australia
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The Alfred Hospital
RECRUITINGMelbourne, Victoria, 3004, Australia
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The Royal Marsden Hospital
RECRUITINGLondon, SM2 5PT, United Kingdom
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University Hospital of Wales
RECRUITINGCardiff, CF14 4XW, United Kingdom
Contact