New hope for elderly leukemia patients: drug duo targets tough-to-treat cancer
NCT ID NCT06389292
First seen Jan 02, 2026 · Last updated May 15, 2026 · Updated 20 times
Summary
This study tests whether adding the experimental drug APG-2575 (Lisaftoclax) to the standard medicine azacitidine helps older adults with newly diagnosed acute myeloid leukemia (AML) live longer. About 486 participants who cannot have strong chemotherapy will receive either the combo or a placebo plus azacitidine. The main goal is to see if the combination improves overall survival.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Botkin Moscow Multidisciplinary Research and Clinical Center
RECRUITINGMoscow, 125284, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hematology Hospital of the Chinese Academy of Medical Sciences
RECRUITINGTianjin, Tianjin Municipality, 300020, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Leningrad Regional Clinical Hospital
RECRUITINGSaint Petersburg, 194291, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Moscow Multidisciplinary Clinical Center "Kommunarka"
RECRUITINGMoscow, 108814, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Russian Research Institute of Hematology and Transfusiology of the Federal Medical and Biological Agency
RECRUITINGSaint Petersburg, 191024, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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The First Affiliated Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310003, China
Contact Phone: •••-•••-••••
Contact Email: •••••@•••••
Contact
Conditions
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