New injection battles chemo sickness in major cancer trial

NCT ID NCT00343460

Completed Symptom relief Sponsor: Heron Therapeutics Source: ClinicalTrials.gov ↗

Summary

This large, completed Phase 3 trial tested if a new drug called APF530 works as well or better than the standard drug Aloxi (palonosetron) to prevent nausea and vomiting in cancer patients receiving chemotherapy. Over 1,400 patients participated, receiving either the new drug or the standard one, along with a steroid, before their chemo. The main goal was to see which treatment better prevented sickness both right after chemo and in the days that followed.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Advanced Research Management Services, Incorporated

Los Angeles, California, 90057, United States
Anniston Oncology, PC

Anniston, Alabama, 36207, United States
Arizona Clinical Research Center, Incorporated

Tucson, Arizona, 85715, United States
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
Boice Willis Clinic, PA

Rocky Mount, North Carolina, 27804, United States
Cancer Center of Indiana

New Albany, Indiana, 47150, United States
Cancer Outreach Associates - Abingdon

Abingdon, Virginia, 24211, United States
Cancer Treatment Centers of America at Southwestern Regional Medical Center

Tulsa, Oklahoma, 74133-4564, United States
Center for Cancer and Blood Disorders at Suburban Hospital

Bethesda, Maryland, 20817, United States
Center for Clinical Research at Washington County Hospital

Hagerstown, Maryland, 21740, United States
Charleston Hematology Oncology Associates, PA

Charleston, South Carolina, 29403, United States
Clintell, Incorporated

Skokie, Illinois, 60077, United States
Columbus Clinic, PC

Columbus, Georgia, 31901, United States
Compassionate Cancer Care Medical Group Incorporated - Corona

Corona, California, 92882, United States
Compassionate Cancer Care Medical Group Incorporated - Fountain Valley

Fountain Valley, California, 92708, United States
Comprehensive Cancer Center at Pardee Hospital

Hendersonville, North Carolina, 28791, United States
Eastern Connecticut Hematology and Oncology Associates

Norwich, Connecticut, 06360, United States
Eastern North Carolina Medical Group, PLLC

Rocky Mount, North Carolina, 27804, United States
Falck Cancer Center at Arnot Ogden Medical Center

Elmira, New York, 14905, United States
Family Medicine of Vincennes Clinical Trial Center

Vincennes, Indiana, 47591, United States
Gabrail Cancer Center - Canton Office

Canton, Ohio, 44718, United States
Gabrail Cancer Center - Dover Office

Dover, Ohio, 44622, United States
Hematology-Medical Oncology Associates at Central Maine Comprehensive Cancer Center

Lewiston, Maine, 04240, United States
Hudson Valley Hematology-Oncology Associates - Poughkeepsie

Poughkeepsie, New York, 12601, United States
Innovative Medical Research of South Florida, Incorporated

North Miami Beach, Florida, 33179-4709, United States
Investigative Clinical Research, LLC

Indianapolis, Indiana, 46254, United States
Julie and Ben Rogers Cancer Institute at Memorial Hermann Baptist Beaumont Hospital

Beaumont, Texas, 77701, United States
Kansas City Cancer Centers - South

Kansas City, Missouri, 64131, United States
Kenmar Research Institute

Los Angeles, California, 90057, United States
Kentuckiana Cancer Institute, PLLC

Louisville, Kentucky, 40202, United States
Kentucky Cancer Clinic - Hazard

Hazard, Kentucky, 41701, United States
Mary Babb Randolph Cancer Center at West Virginia University Hospitals

Morgantown, West Virginia, 26506-9300, United States
McDowell Cancer Center at Akron General Medical Center

Akron, Ohio, 44302, United States
MedCentral - Mansfield Hospital

Mansfield, Ohio, 44903, United States
Medical Center Vincennes

Vincennes, Indiana, 47591, United States
Medical Oncology Care Associates - Orange

Orange, California, 92868, United States
Mercy Medical Center

Baltimore, Maryland, 21202-2165, United States
MultiCare Regional Cancer Center at Tacoma General Hospital

Tacoma, Washington, 98405, United States
Northern Michigan Hospital

Petoskey, Michigan, 49770, United States
Pacific Cancer Medical Center, Incorporated

Anaheim, California, 92801, United States
Palo Verde Hematology Oncology - Glendale

Glendale, Arizona, 85304, United States
Pasco Pinellas Cancer Center - New Port Richey

New Port Richey, Florida, 34689, United States
Pottsville Cancer Clinic

Pottsville, Pennsylvania, 17901, United States
Providence Hospital

Washington D.C., District of Columbia, 20017, United States
Regional Cancer Center at Singing River Hospital

Pascagoula, Mississippi, 39581, United States
Signal Point Hematology Oncology Incorporated

Middletown, Ohio, 45042, United States
Southbay Oncology / Hematology Medical Group

Campbell, California, 95008, United States
Star Hematology & Oncology

Phillipsburg, New Jersey, 08865, United States
Texas Cancer Clinic

San Antonio, Texas, 78240, United States
Veterans Affairs Medical Center - Buffalo

Buffalo, New York, 14215, United States
Virginia Oncology Care, PC

Richlands, Virginia, 24641, United States
Western Washington Oncology, Incorporated, PS at Western Washington Cancer Center

Lacey, Washington, 98503, United States

Conditions

Explore the condition pages connected to this study.

NAUSEA AND VOMITING UNSPECIFIED ADULT SOLID TUMOR, PROTOCOL SPECIFIC