Heart study challenges when to operate on 'Ticking time Bomb' aorta

NCT ID NCT03536312

Summary

This trial aims to find the best approach for people with a moderately enlarged aorta, a condition that risks a dangerous tear. About 610 participants will be randomly assigned to either have early surgery to replace the aorta or to be closely monitored with regular scans. The study will compare which group has fewer deaths or aortic emergencies over two years to guide future treatment decisions.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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  • Contact

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Locations

  • Baylor Scott & White Research Institute

    RECRUITING

    Plano, Texas, 75093, United States

    Contact

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University

    RECRUITING

    Durham, North Carolina, 27705, United States

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  • Hamilton General Hospital

    RECRUITING

    Hamilton, Ontario, Canada

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  • Health Sciences North

    RECRUITING

    Greater Sudbury, Ontario, Canada

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  • Horizon Health Network

    RECRUITING

    Saint John, New Brunswick, E2L 4L2, Canada

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  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

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  • Institut universitaire de cardiologie et de pneumologie de Québec

    RECRUITING

    Québec, Quebec, G1V 4G5, Canada

    Contact

  • London Health Sciences Centre

    RECRUITING

    London, Ontario, N6A 5A5, Canada

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  • MUSC Health University Medical Center

    RECRUITING

    Charleston, South Carolina, 29425, United States

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  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

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  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Mazankowski Alberta Heart Institute

    RECRUITING

    Edmonton, Alberta, T6G 0M9, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • McGill University Health Centre

    RECRUITING

    Montreal, Quebec, H3H2R9, Canada

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  • Montreal Heart Institute

    RECRUITING

    Montreal, Quebec, H1T 1C8, Canada

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  • Nova Scotia Health Authority

    RECRUITING

    Halifax, Nova Scotia, B3S 0H6, Canada

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    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

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  • St. Michael's Hospital

    NOT_YET_RECRUITING

    Toronto, Ontario, M5B 1W8, Canada

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  • The Trustees of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

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  • The Valley Hospital, Inc

    RECRUITING

    Ridgewood, New Jersey, 07652, United States

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  • Toronto General Hospital

    RECRUITING

    Toronto, Ontario, Canada

    Contact

  • University Hospitals Cleveland

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 2T9, Canada

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  • University of California at San Francisco Medical Center

    RECRUITING

    San Francisco, California, 94121, United States

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  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

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  • University of Ottawa Heart Institute

    RECRUITING

    Ottawa, Ontario, K1Y 4W7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • University of Texas Health Science Centre

    RECRUITING

    Houston, Texas, 77030, United States

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  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.