New eye injection aims to halt blinding disease in seniors

NCT ID NCT06510816

Ongoing Disease control Sponsor: Annexon, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing if a new drug called ANX007, given as a monthly injection into the eye, can slow down vision loss in people with geographic atrophy, a late-stage form of age-related macular degeneration. About 660 participants will be randomly assigned to receive either the real injection or a sham (pretend) procedure to see if the treatment is effective. The main goal is to see if the treatment reduces the number of people who lose a significant amount of reading vision over time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

ASST Fatebenefratelli Sacco

Milan, 20157, Italy
Alberta Retina Consultants

Edmonton, Alberta, T5H 0X5, Canada
Asheville Eye Associates - Retina Division

Asheville, North Carolina, 28803, United States
Augenzentrum am St. Franziskus-Hospital

Münster, North Rhine-Westphalia, 48145, Germany
Austin Clinical Research, LLC

Austin, Texas, 78750, United States
Austin Research Center for Retina

Austin, Texas, 78705, United States
Austin Retina Associates

Austin, Texas, 78705, United States
Axon Clinical, s.r.o. Ocni Klinika

Prague, 150 00, Czechia
Azienda Ospedaliera Universitaria Careggi

Florence, 50134, Italy
Bay Area Retina Associates

Walnut Creek, California, 94598, United States
Budapest Retina Associates

Budapest, 1133, Hungary
CHU Dijon Bourgogne - Hôpital François Mitterrand

Dijon, 21079, France
Calgary Retina Consultants

Calgary, Alberta, T2H 0C8, Canada
Caminomed Sp. Z O.O.

Tarnowskie Góry, 42-600, Poland
Capital Eye Specialists

Te Aro, Wellington Region, 6011, New Zealand
Cascade Medical Research Institute

Springfield, Oregon, 97477, United States
Centre Hospitalier Universitaire de Nice

Nice, 06001, France
Centre Monticelli Paradis d'Ophtalmologie

Marseille, France
Centre Ophtalmologique Maison Rouge

Strasbourg, 67000, France
Centre Ophtalmologique Pôle Vision Val d'Ouest

Écully, France
Centrum Diagnostyki I Mikrochirurgii Oka Lens Sp. Z O.O.

Olsztyn, 10-424, Poland
Charleston Neuroscience Center

Charleston, South Carolina, 29414, United States
Clínica Baviera

Madrid, 28046, Spain
Cumberland Valley Retina Consultants

Hagerstown, Maryland, 21740, United States
Debreceni Egyetem Klinikai Kozpont Nagyerdei Campus

Debrecen, 4032, Hungary
Dietrich Bonhoeffer Klinikum Klinik für Augenheilkunde

Neubrandenburg, Mecklenburg-Vorpommern, 17036, Germany
East Florida Eye Institute

Stuart, Florida, 34994, United States
Elisabeth Hospital (ETZ) - location TweeSteden ziekenhuis

Tilburg, 5042 AD, Netherlands
Envision Ocular, LLC

Bloomfield, New Jersey, 07003, United States
Erie Retina Research, LLC

Erie, Pennsylvania, 16507, United States
Eye Care Specialists

Kingston, Pennsylvania, 18704, United States
Eye Clinic Albury Wodonga

Albury, New South Wales, 2640, Australia
Eye Clinic of Wisconsin

Wausau, Wisconsin, 54403, United States
Eyehealth Northwest Portland

Portland, Oregon, 97209, United States
Fakultní nemocnice Královské Vinohrady

Prague, 100 34, Czechia
Florida Retina Institute

Orlando, Florida, 32806, United States
Fondazione G.B. Bietti Per Lo Sudio E La Ricerca In Oftalmologia - Presidio

Roma, 00184, Italy
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

Milan, 20122, Italy
Fondazione PTV Policlinico Tor Vergata

Rome, 00133, Italy
Fondazione Policlinico Agostino Gemelli

Rome, 00168, Italy
Fort Lauderdale Eye Institute

Plantation, Florida, 33324, United States
Ganglion Medical Center

Pécs, 7681, Hungary
Georgia Retina PC

Marietta, Georgia, 30060, United States
Global Research Management

Glendale, California, 91204, United States
Groupe Hospitalier Pellegrin - CHU de Bordeaux

Bordeaux, 33076, France
Hospital Clinico Universitario de Santiago

Santiago de Compostela, 15706, Spain
Hospital Universitari General de Catalunya - Grupo Quironsalud

Sant Cugat del Vallès, 08195, Spain
Hospital Universitari Vall d'Hebron

Barcelona, 08035, Spain
Hospital Universitario Miguel Servet

Zaragoza, 50009, Spain
Hospital Universitario Puerta de Hierro - Majadahonda

Majadahonda, 28222, Spain
Hospital Universitario Virgen Macarena

Seville, 41009, Spain
Hospital de la Arruzafa - Metavisión Arruzafa

Córdoba, 14012, Spain
Hôpital Lariboisière - Service d'ophtalmologie

Paris, 75010, France
IRCCS MultiMedica

Milan, 20123, Italy
IRCCS Ospedale San Raffaele

Milan, 20132, Italy
Institut Català de Retina

Barcelona, 08017, Spain
Ivey Eye Institute

London, Ontario, N6A 4V2, Canada
Kepler Universitätsklinikum

Linz, 4020, Austria
King's College Hospital

London, SE5 9RS, United Kingdom
Klinikum Klagenfurt am Wörthersee

Klagenfurt, 9020, Austria
Long Island Vitreoretinal Consultants

Hauppauge, New York, 11788, United States
Macula Retina Vitreous Research Institute

Torrance, California, 90503, United States
Maine Eye Center

Portland, Maine, 04101, United States
Marsden Eye Specialists

Parramatta, New South Wales, 2150, Australia
Mid Atlantic Retina

Cherry Hill, New Jersey, 08034, United States
Mid Atlantic Retina Specialists

Hagerstown, Maryland, 21740, United States
Moorfields Eye Hospital NHS foundation Trust

London, EC1V 2PD, United Kingdom
National Ophthalmic Research Institute

Fort Myers, Florida, 33912, United States
North Carolina Retina Associates

Cary, North Carolina, 27511, United States
North Carolina Retina Associates

Wake Forest, North Carolina, 27587, United States
Northern California Retina Vitreous Associates Medical Group, Inc.

Mountain View, California, 94040, United States
Oftalmika Sp.Zo.O.

Bydgoszcz, 85-631, Poland
Oftalvist IMED Burjassot

Valencia, Burjasso, 46100, Spain
Ophthalmic Consultants of Boston

Boston, Massachusetts, 02114, United States
Ośrodek Chirurgii Oka Prof. Zagórskiego Sp. Z o.o.

Rzeszów, 35-017, Poland
Palmetto Retina Center

Aiken, South Carolina, 29801, United States
Piedmont Eye Center

Lynchburg, Virginia, 24502, United States
Piedmont Retina Specialists - Winston Salem Office

Winston-Salem, North Carolina, 27103, United States
RCOC Clinical Research Institute Inc

Fullerton, California, 92835, United States
RSC Research, LLC

Denver, Colorado, 80222, United States
Rand Eye Institute

Deerfield Beach, Florida, 33064, United States
Retina Associates - Elmhurst Location

Elmhurst, Illinois, 60126, United States
Retina Centre of Ottawa

Ottawa, Ontario, K2B 7E9, Canada
Retina Consultants Medical Group

Modesto, California, 95356, United States
Retina Consultants of Hawaii

‘Aiea, Hawaii, 96701, United States
Retina Consultants of Minnesota

Saint Louis Park, Minnesota, 55416, United States
Retina Consultants of Southern Colorado PC

Colorado Springs, Colorado, 80909, United States
Retina Consultants of Texas

Bellaire, Texas, 77401, United States
Retina Consultants of Texas

Katy, Texas, 77494, United States
Retina Consultants of Texas

The Woodlands, Texas, 77384, United States
Retina Consultants of Texas San Antonio

San Antonio, Texas, 78240, United States
Retina Foundation of the Southwest

Dallas, Texas, 75231, United States
Retina Group of Florida

Sarasota, Florida, 34233, United States
Retina Group of Washington

Chevy Chase, Maryland, 20815, United States
Retina Macula Institute of Arizona

Scottsdale, Arizona, 85255, United States
Retina Research Institute at New England Retina Consultants

Springfield, Massachusetts, 01107, United States
Retina Research Institute of Texas

Abilene, Texas, 79606, United States
Retina Vitreous Associates of Florida

St. Petersburg, Florida, 33711, United States
Retina Vitreous Center

Edmond, Oklahoma, 73013, United States
Retina-Vitreous Associates Medical Group

Beverly Hills, California, 90211, United States
Retinal Consultants Medical Group

Sacramento, California, 95825, United States
ReƟna Consultants of Charleston

Beaufort, South Carolina, 29901, United States
Rocky Mountain Retina Consultants

Salt Lake City, Utah, 84107, United States
Semmelweis Egyetem

Budapest, 1085, Hungary
Service d'Ophtalmologie Centre Hospitalier Intercommunal de Créteil

Créteil, 94000, France
Sierra Eye Associates

Reno, Nevada, 89502, United States
Southeastern Retina

Chattanooga, Tennessee, 37604, United States
Southern Eye Specialists

Christchurch, Canterbury, 8013, New Zealand
Southwest Retina Specialists

Amarillo, Texas, 79106, United States
Springfield Clinic LLP

Springfield, Illinois, 62703, United States
Strategic Clinical Research Group, LLC

Willow Park, Texas, 76087, United States
Strathfield Retina Clinic

Melbourne, New South Wales, 2135, Australia
Sydney Eye Hospital

Sydney, New South Wales, 2000, Australia
Sydney Retina Clinic and Day Surgery

Sydney, New South Wales, 2000, Australia
Tennessee Retina PC

Nashville, Texas, 37203, United States
Texas Retina Associates

Fort Worth, Texas, 76104, United States
Texas Retina Associates - Plano

Dallas, Texas, 75231, United States
Texas Retina Associates- Arlington

Arlington, Texas, 76012, United States
The Retina Clinic

London, W1G 9AX, United Kingdom
Tulsa Retina Consultants

Tulsa, Oklahoma, 74114, United States
Uni-Augenklinik Bonn

Bonn, 53127, Germany
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University Retina

Oak Forest, Illinois, 60452, United States
Universitätsklinikum Heidelberg

Heidelberg, 69120, Germany
Universitätsklinikum Tübingen, Department für Augenheilkunde

Tübingen, 72076, Germany
Verum Research, LLC

Eugene, Oregon, 97401, United States
Vision Research Center Eye Associates of New Mexico

Albuquerque, New Mexico, 87109, United States
Všeobecná fakultní nemocnice V Praze

Prague, 128 08, Czechia
Warszawski Szpital Okulistyczny

Warsaw, 01-258, Poland
Wolfe Eye Clinic

West Des Moines, Iowa, 50266, United States

Conditions

Explore the condition pages connected to this study.

GEOGRAPHIC ATROPHY