New hope for heart surgery patients whose blood thinners fail
NCT ID NCT06096116
First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 28 times
Summary
This study tests a medicine called Atenativ in 120 adults having heart surgery who do not respond well to the standard blood thinner heparin. The goal is to see if Atenativ can restore heparin's effectiveness during surgery, reducing the need for extra treatments. Participants will receive either Atenativ or a placebo, and researchers will monitor how well their blood thins during the procedure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atrium Health Wake Forest Baptist
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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CHU de Reims, Hôpital Robert Debré
TERMINATEDReims, France
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CHU de Rennes
WITHDRAWNRennes, France
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Center of Cardiovascular and Transplant Surgery
RECRUITINGBrno, Czechia
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Cleveland Clinic
NOT_YET_RECRUITINGCleveland, Ohio, 44195, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710-1000, United States
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Hospital of Lithuanian university of Health sciences Kauno Klinikos
RECRUITINGKaunas, Lithuania
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Institute for Cardiovascular Diseases C.C. Iliescu
RECRUITINGBucharest, Romania
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Institute for Clinical and Experimental Medicine
RECRUITINGPrague, Czechia
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Institute of Cardiovascular Diseases Vojvodina
NOT_YET_RECRUITINGKamenitz, Serbia
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Kingston Health Sciences Centre
RECRUITINGKingston, Ontario, K7L2V7, Canada
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Montreal Heart Institute
RECRUITINGMontreal, Quebec, H1T1C8, Canada
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OU Health University of Oklahoma Medical Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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Royal Columbian Hospital
RECRUITINGNew Westminster, British Columbia, V3L0A4, Canada
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Royal Papworth Hospital
RECRUITINGCambridge, United Kingdom
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Stanford University School of Medicine
RECRUITINGStanford, California, 94305-5101, United States
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The James Cook University Hospital
RECRUITINGMiddlesbrough, United Kingdom
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The Ohio State University
RECRUITINGColumbus, Ohio, 43214, United States
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Toronto General Hospital
RECRUITINGToronto, Ontario, M5G2C4, Canada
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University Hospital Coventry and Warwickshire
RECRUITINGCoventry, United Kingdom
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University Hospital Innsbruck
RECRUITINGInnsbruck, Austria
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University Medical Centre Ljubljana
RECRUITINGLjubljana, Slovenia
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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University of Texas Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Vienna General Hospital AKH, Medical University of Vienna
RECRUITINGVienna, Austria
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Vilnius University hospital Santaros Klinikos
RECRUITINGVilnius, Lithuania
Conditions
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