New drug shows promise against dangerous virus in kidney transplants

NCT ID NCT05769582

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 26 times

Summary

This study tested a drug called AntiBKV in 95 kidney transplant patients who had a BKV infection. The goal was to see if it could safely lower the virus levels and prevent kidney damage. Patients received four doses of the drug or a placebo over several weeks, with regular check-ups and biopsies to monitor results.

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Contacts and locations

Locations

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Hartford Hospital

    Hartford, Connecticut, 06105, United States

  • Harvard Medical School

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Transplant Center

    Jacksonville, Florida, 32224, United States

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • Metrolina Nephrology Associates (MNA), PA

    Charlotte, North Carolina, 28207, United States

  • New York Presbyterian Hospital - Weill Cornell Medical Center

    New York, New York, 10065, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Saint Barnabas Medical Center

    Livingston, New Jersey, 07039, United States

  • UT Southwestern

    Dallas, Texas, 75390, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of California Davis

    Sacramento, California, 95817, United States

  • University of California, Los Angeles

    Los Angeles, California, 90024, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Maryland

    Baltimore, Maryland, 21201, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania Hospital of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

  • Washington University School of Medicine in St. Louis

    St Louis, Missouri, 63110, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06520, United States

Conditions

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