New trial aims to end surgery for rare breast disease
NCT ID NCT07454772
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether antibiotics or steroids work better for granulomatous lobular mastitis, a rare inflammatory breast condition that mostly affects young women after childbirth. Seventy-two participants will receive either an 8-week course of antibiotics or tapering doses of steroids. The goal is to find which treatment leads to faster healing with fewer side effects, potentially creating a standard care plan and reducing the need for surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Prednisolone (steroid) and a combination of clarithromycin, ofloxacin, and rifaximin (antibiotics)
- What this could lead to
- If successful, this study could establish a standard treatment protocol for granulomatous lobular mastitis, reducing the need for surgery and improving recovery for affected women.
- What could go wrong
- This is an early-phase trial with only 72 participants, so results may not apply to everyone. Both treatments have side effects, and some patients may not respond to either option.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GRANULOMATOUS MASTITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AIIMS Bhubaneswar
Bhubaneswar, Odisha, 751019, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.