Antibiotics may temporarily alter gut nerve cells, new study finds

NCT ID NCT05834036

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at how a short course of antibiotics changes the nerve and glia cells in the lower gut of 10 healthy adults. Researchers took colon tissue samples before and after antibiotic treatment to count these cells and measure gene activity. The goal was to understand if antibiotics can temporarily affect the gut's nervous system, which may help explain digestive issues after antibiotic use.

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Conditions

The condition(s) this trial relates to.

Clostridium difficile colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rockefeller University

    New York, New York, 10065, United States