Could an antibiotic beat eye cancer? new trial tests doxycycline for lymphoma
NCT ID NCT01820910
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tested the antibiotic doxycycline as a first treatment for a rare type of eye lymphoma (OAMZL) that may be linked to a bacterial infection. 44 newly diagnosed patients took doxycycline for several months. The goal was to see if eradicating the infection could control the lymphoma and delay or avoid the need for stronger treatments like chemotherapy or radiation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
doxycycline
What this could lead to
If successful, this antibiotic approach could provide a less toxic, chemotherapy-free treatment option for this rare eye lymphoma.
What could go wrong
This is a small, early-phase trial (44 people) without a comparison group. The lymphoma may not respond or could return after treatment.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AO Ospedali Riuniti Papardo Piemonte
Messina, Italy
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Ematologia
Parma, Italy
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Molinette 1
Torino, Italy
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Ospedale Civile
Piacenza, Italy
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Ospedale San Raffaele
Milan, Italy
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Ospedale dell'Angelo
Venezia, Italy
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Spedali Civili Di Brescia
Brescia, Italy
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Università La Sapienza
Rome, Italy