Could one antibiotic replace two for chemo fevers? major trial launches.

NCT ID NCT07483736

First seen Mar 25, 2026 · Last updated May 14, 2026 · Updated 6 times

Summary

This study tests whether a single antibiotic (amoxicillin-clavulanate) works as well as the usual two-antibiotic combination for treating fever caused by chemotherapy in adults with certain blood cancers. About 1,526 participants will be randomly assigned to one of the two treatments. The goal is to see if the simpler approach is just as effective, while reducing side effects and antibiotic resistance.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Jacques Coeur

    Bourges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH Poissy Saint-Germain-en-Laye

    Poissy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de BRIVE LA GAILLARDE

    Brive-la-Gaillarde, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de Perigueux

    Périgueux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de SAINT NAZAIRE

    Saint-Nazaire, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de SAUMUR

    Saumur, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de Valence

    Valence, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH de Versailles

    Le Chesnay, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Caen-Normandie

    Caen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU d'ORLEANS

    Orléans, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de SAINT-ETIENNE

    Saint-Priest-en-Jarez, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Groupe Hospitalier Haute Saône Vesoul

    Vesoul, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital Necker Enfants Malade

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital Saint Louis

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital de La Pitie Salpetriere

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Curie

    Saint-Cloud, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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