Joint surgery infection breakthrough? powder plus IV antibiotics tested on 1,832 patients

NCT ID NCT04399642

First seen Oct 31, 2025 · Last updated Jun 05, 2026 · Updated 34 times

Summary

This study looks at whether adding antibiotic powder directly into the joint during hip or knee replacement surgery can reduce infections better than just giving antibiotics through an IV. About 1,832 adults having a first-time or aseptic revision joint replacement will be randomly assigned to one of two groups. The goal is to see if the extra antibiotic powder helps prevent short- and long-term infections.

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Contacts and locations

Locations

  • Hopital Sacré-Coeur de Montreal

    Montreal, Quebec, H4J 1C5, Canada

Conditions

Explore the condition pages connected to this study.