Engineered immune cells take on rare leukemia in first human trial
NCT ID NCT04815356
First seen Nov 11, 2025 · Last updated Apr 25, 2026 · Updated 23 times
Summary
This early-phase study tests whether a customized immune cell therapy (anti-CD22 CAR T cells) is safe for people with hairy cell leukemia (classic or variant) that has returned or not responded to standard treatments. Up to 27 adults will receive the therapy after mild chemotherapy. The goal is to check for side effects and see if the treatment can shrink the cancer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-••••
Conditions
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