Engineered immune cells take on rare leukemia in first human trial
NCT ID NCT04815356
First seen Nov 11, 2025 · Last updated Jun 14, 2026 · Updated 29 times
Summary
This early-phase study tests whether a new type of immunotherapy, called anti-CD22 CAR T cells, is safe for people with hairy cell leukemia (HCL) that has come back or not responded to standard treatments. Up to 27 adults will have their own immune cells collected, modified in a lab to recognize and attack cancer cells, and then infused back after mild chemotherapy. The main goals are to check for side effects and see if the treatment can shrink tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-••••
Conditions
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