Experimental CAR-T therapy targets Hard-to-Treat cancers in small pilot study

NCT ID NCT04627740

First seen Jan 23, 2026 · Last updated Jun 11, 2026 · Updated 25 times

Summary

This early-stage study tested a new type of immune cell therapy (CAR-T cells) designed to attack a protein called ALPP found on some advanced solid tumors. Five patients with tumors that had not responded to standard treatments received the therapy. The main goals were to check for side effects and see if the treatment could shrink tumors or slow their growth.

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Contacts and locations

Locations

  • Department of Oncology, Xinqiao Hospital

    Chongqing, Chongqing Municipality, 400037, China

Conditions

Explore the condition pages connected to this study.