New hope for advanced colon cancer patients in major trial

NCT ID NCT04854668

Ongoing Disease control Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 trial is comparing two different drug combinations as first treatment for advanced colorectal cancer that has spread and has specific genetic markers (RAS/BRAF wild-type). 748 participants will receive either the experimental combination (anlotinib plus chemotherapy) or the standard combination (bevacizumab plus chemotherapy). The study aims to see if the new combination helps control cancer growth longer and is safe for patients.

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Contacts and locations

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Locations

3201 Hospital

Hanzhong, Shaanxi, 723000, China
Affiliated Hospital of Chifeng University

Chifeng, Inner Mongolia, 024000, China
Affiliated Hospital of Guangdong Medical University

Zhanjiang, Guangdong, 524000, China
Affiliated Hospital of Jiangnan University

Wuxi, Jiangsu, 214062, China
Affiliated Hospital of Jining Medical University

Jining, Shandong, 272001, China
Affiliated Tumor Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, 830000, China
Anhui Cancer Hospital

Hefei, Anhui, 230031, China
Anhui Provincial Hospital

Hefei, Anhui, 230001, China
Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, 100050, China
Cancer Hospital of Shantou University Medical College

Shantou, Guangdong, 515031, China
Changzhi People's Hospital

Changzhi, Shanxi, 46000, China
Chifeng Municipal hospital

Chifeng, Inner Mongolia, 024000, China
China-Japan Friendship Hospital

Beijing, Beijing Municipality, 100029, China
First Affiliated Hospital of Xinjiang Medical University

Ürümqi, Xinjiang, 830000, China
Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, 200032, China
Fujian Cancer Hospital

Fuzhou, Fujian, 350011, China
Fujian Medical University Union Hospital

Fuzhou, Anhui, 350011, China
Fuling Hospital Affiliated to Chongqing University

Chongqing, Chongqing Municipality, 408099, China
Gansu Provincial Cancer Hospital

Lanzhou, Gansu, 730000, China
Gansu Provincial Hospital

Lanzhou, Gansu, 730000, China
Genertec Liaoyou Gem Flower Hospital

Panjin, Liaoning, 124009, China
Guizhou Provincial People's Hospital

Guiyang, Guizhou, 550002, China
Hanzhong Central Hospital

Hanzhong, Shaanxi, 723000, China
Harbin Medical University Affiliated Cancer Hospital

Harbin, Heilongjiang, 150000, China
Henan Cancer Hospital

Zhengzhou, Henan, 450008, China
Huaihe Hospital of Henan University

Kaifeng, Henan, 475000, China
Hubei Cancer Hospital

Wuhan, Hubei, 430079, China
Hunan Cancer Hospital

Changsha, Hunan, 410013, China
Huzhou Cancer Hospital

Huzhou, Zhejiang, 313099, China
Inner Mongolia Autonomous Region Cancer Hospital

Hohhot, Neimenggu, 170000, China
JiangXi PingXiang People's Hospital

Pingxiang, Jiangxi, 337055, China
Jiangsu Cancer hospital

Nanjing, Jiangsu, 210009, China
Jiangsu Province People's Hospital

Nanjing, Jiangsu, 210029, China
Jiangsu Taizhou People's Hospital

Taizhou, Jiangsu, 225300, China
Jilin Cancer Hospital

Changchun, Jilin, 130012, China
Jilin Province FAW General Hospital

Changchun, Jilin, 130011, China
Lanzhou University Second Hospital

Lanzhou, Gansu, 730030, China
Liaocheng People's Hospital

Liaocheng, Shandong, 252000, China
Liaoning Cancer Hospital

Shenyang, Liaoning, 110801, China
Liuzhou Workers' Hospital

Liuchow, Guangxi, 545007, China
Longhua Hospital Shanghai University of Traditional Chinese Medicine

Shanghai, Shanghai Municipality, 200032, China
Meihekou Central Hospital

Meihekou, Jilin, 135022, China
Nanjing First Hospital

Nanjing, Jiangsu, 210012, China
Nanjing Hospital of C.M.

Nanjing, Jiangsu, 210022, China
Nanyang Second General Hospital

Nanyang, Henan, 473000, China
Peking University BinHai Hospital

Tianjin, Tianjin Municipality, 300450, China
Peking University Frist Hospital

Beijing, Beijing Municipality, 100034, China
Qinghai University Affiliated Hospital

Xining, Qinghai, 810000, China
Qingyuan People's Hospital

Qingyuan, Guangdong, 511518, China
Shaanxi Provincial People's Hospital

Xi'an, Shaanxi, 710068, China
Shandong Cancer Hospital Affiliated to Shandong Univercity

Jinan, Shandong, 250117, China
Shanghai General Hospital

Shanghai, Shanghai Municipality, 200080, China
Shanghai Tenth People's Hospital

Shanghai, Shanghai Municipality, 200032, China
Shanxi Provincial Cancer Hospital

Taiyuan, Shanxi, 030000, China
Shanxi Provincial People's Hospital

Taiyuan, Shanxi, 030000, China
Shengjing Hospital of China Medical University

Shenyang, Liaoning, 110000, China
Subei People's Hospital of Jiangsu Province

Yangzhou, Jiangsu, 225001, China
Taizhou Second People's Hospital

Taizhou, Jiangsu, 225300, China
Tangshan People's Hospital

Tangshan, Hebei, 63001, China
The Affiliated Cancer Hospital of Guizhou Medical University

Guiyang, Guizhou, 550000, China
The First Affiliatde Hospital of DaLin Medical University

Dalian, Liaoning, 116011, China
The First Affiliated Hospital Of Guangzhou Medical University

Guangzhou, Guangdong, 510120, China
The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400042, China
The First Affiliated Hospital of Hebei North University

Zhangjiakou, Hebei, 75000, China
The First Affiliated Hospital of Henan University of Science and Technology

Luoyang, Henan, 471000, China
The First Affiliated Hospital of Jinzhou Medical University

Jinzhou, Liaoning, 121012, China
The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, 710068, China
The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, 361003, China
The First Affiliated Hospital of ZhengZhou University

Zhengzhou, Henan, 45000, China
The First Hospital of China Medical University

Shenyang, Liaoning, China
The First Hospital of Lanzhou University

Lanzhou, Gansu, 730030, China
The First Hospital of Qinhuangdao

Qinhuangdao, Hebei, 660000, China
The First People's Hospital of Kashgar

Kashgar, Xinjiang, 844000, China
The First Peoples Hospital of Changzhou

Changzhou, Jiangsu, 213000, China
The People's Hospital of Chizhou

Chizhou, Anhui, 247000, China
The Second Affiliated Hospital Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310009, China
The Second Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, 150086, China
The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, 330000, China
The Second Affiliated Hospital of PLA Air Force Military Medical University

Xi'an, Shaanxi, 710068, China
Tianjin Medical University Cancer Institute and Hospital

Tianjin, Tianjin Municipality, 300060, China
Tongji Hospital Affiliated to Tongji Medical College Hust

Wuhan, Hubei, 430030, China
Weifang Hospital of Traditional Chinese Medicine

Weifang, Shandong, 261041, China
Xi'an International Medical Center Hospital

Xi'an, Shaanxi, 710061, China
Xiangyang Central Hospital

Xiangyang, Hubei, 441021, China
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, 200080, China
Xinyang Central Hospital

Xinyang, Henan, 464099, China
Xuancheng People's Hospital

Xuancheng, Anhui, 242000, China
Yanbian University Hospital

Yanji, Jilin, 133099, China
Yantai Yuhuangding Hospital

Yantai, Shandong, 264000, China
Yunnan Cancer Hospital

Kunming, Yunnan, 650118, China
Zhejiang Cancer Hospital

Hangzhou, Zhejiang, 310022, China
Zhongda Hospital Southeast University

Nanjing, Jiangsu, 210009, China

Conditions

Explore the condition pages connected to this study.

METASTATIC COLORECTAL CANCER