New drug shows promise for back pain from ankylosing spondylitis

NCT ID NCT07498634

First seen Apr 04, 2026 · Last updated May 02, 2026 · Updated 6 times

Summary

This study tested a new antibody drug (XKH004) in 323 adults with moderate-to-severe active ankylosing spondylitis, a type of arthritis that causes back pain and stiffness. The drug aims to reduce inflammation by blocking certain proteins. Participants received either the drug or a placebo, and the main goal was to see if more people on the drug had a 40% improvement in symptoms after 16 weeks.

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Contacts and locations

Locations

  • Shanghai Changzheng Hospital

    Shanghai, China

Conditions

Explore the condition pages connected to this study.