Brain injection gene therapy offers hope for rare neurological disorder

NCT ID NCT07181837

Summary

This early-stage trial is testing whether a single injection of experimental gene therapy (MVX-220) into the fluid around the brain can help people with Angelman syndrome. The study will enroll 12 children and adults to first check safety, then see if the treatment improves communication, development, and daily functioning. All participants will receive the gene therapy and be followed for five years to monitor long-term effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cedars-Sinai Medical Center

    RECRUITING

    Los Angeles, California, 90048, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.