Which anesthesia is safest for your brain after surgery? new study in obese patients

NCT ID NCT07665645

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study looked at how different types of anesthesia affect thinking and memory after surgery in 90 obese patients. Patients received either low-flow sevoflurane gas, normal-flow sevoflurane gas, or total intravenous anesthesia with propofol and remifentanil. Their cognitive function was tested before surgery, 30 minutes after, and on the third day after surgery. The goal is to find out which method might be best for protecting brain function in obese patients.

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Contacts and locations

Locations

  • Marmara University Faculty of Medicine Pendik Training and Research Hospital

    Istanbul, Istanbul, 34899, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sevoflurane, propofol, remifentanil

What this could lead to

If this study shows clear differences, it could help doctors choose the best anesthesia for obese patients to protect their memory and thinking after surgery.

What could go wrong

This is a small, completed study with only 90 participants. The results may not apply to all obese patients or surgeries, and the cognitive test used is basic.

Conditions

The condition(s) this trial relates to.

Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.