Scientists map the hidden timeline of a deadly hantavirus
NCT ID NCT07703579
First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time
Summary
This observational study follows people who have been exposed to Andes virus, a hantavirus that can cause severe respiratory illness. Researchers collect blood samples and monitor symptoms at key points from exposure through infection and recovery. The goal is to understand how the virus behaves in the body and how the immune system responds, without directing any medical care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal key patterns in how Andes virus infection progresses, helping design better treatments or vaccines for hantavirus diseases.
- What could go wrong
- This is a small observational study with only 15 participants, so findings may not apply broadly. It does not test any treatment, so it cannot directly improve patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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15 people
The number who actually took part.
- Started
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May 2026
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consenting persons of any age who have a confirmed exposure to Andes virus and persons with confirmed Andes virus infection who are placed under confinement or quarantine or clinical care for active Andes virus infection. Participation in the NAVIS protocol does not restrict or prevent enrollment in other Hantavirus-related emergency responses or interventional clinical trials.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. No age restriction. 2. Persons diagnosed with or exposed to Andes Virus (ANDV). Exposure must comply with the national definition of ANDV exposure in each country, or satisfy at least one of the following criteria: 1. Direct physical exposure to a person with ANDV infection 2. Environmental and proximity exposure to a person with ANDV infection, i.e.: * Prolonged presence in an enclosed or poorly ventilated shared airspace. Note: Prolonged exposure is defined as cumulative exposure of 15 minutes or more within a 24-hour period in a confined space, or shared occupancy of an enclosed environment for more than 2 hours (ECDC). * Co-habitation in the same household, room, or cabin (e.g., maritime or shared residential settings). * Documented proximity during long-haul travel exceeding 4 hours. Note: Proximity is defined as sitting in an adjacent seat, defined as the same row or within two rows in front or behind. Long haul travel includes flight, bus, car or train. See Box 2 for justification of the 4 hour time threshold. 3. Occupational or caregiving exposure * Provision of direct healthcare or personal care to a person with ANDV infection without the consistent use of recommended Personal Protective Equipment (PPE). * Direct handling of potentially contaminated fomites, such as soiled linens, clothing, or bedding used by a confirmed case. * Direct handling of laboratory samples form a confirmed case with noncompliance with standard biosafety protocols. 3. Ability to comply with confinement sampling and follow up procedures. 4. Informed consent by participant, parent/legal guardian, or surrogate where allowed and applicable; assent or consent for children aged \<18 years or \<16 years as per local regulations. Exclusion Criteria: * 1\. Current imprisonment (quarantine does not count).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Bichat
Paris, 75018, France
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Hôpital Pellegrin
Bordeaux, 75018, France
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La Pitié Salpêtrière
Paris, 75018, France