New injection shows promise for severe eczema in major trial

NCT ID NCT06130566

Completed Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study tested an injectable drug called amlitelimab for people aged 12 and older with moderate-to-severe atopic dermatitis (eczema) that wasn't well-controlled by creams. Over 600 participants were randomly assigned to receive either the drug or a placebo injection for 24 weeks to see if it could clear skin and reduce severe itching. The main goal was to measure how well the treatment worked and how safe it was compared to a dummy treatment.

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Contacts and locations

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Locations

Beth Israel Deaconess Medical Center - Fort Myers- Site Number : 8401286

Fort Myers, Florida, 33919, United States
CCBR / IBPClin - Instituto Brasil de Pesquisa Clínica- Site Number : 0760018

Rio de Janeiro, 22241-180, Brazil
CHEAR Center- Site Number : 8401123

The Bronx, New York, 10459, United States
Carbon Health - North Hollywood - NoHo West- Site Number : 8401218

North Hollywood, California, 91606, United States
Center for Dermatology Clinical Research- Site Number : 8401018

Fremont, California, 94538, United States
Centro de Desenvolvimento em Estudos ClÌnicos Brasil- Site Number : 0760014

São Paulo, 04020-060, Brazil
Centro de Pesquisas da Clínica IBIS- Site Number : 0760002

Salvador, Estado de Bahia, 41820-020, Brazil
Cleaver Medical Group Dermatology- Site Number : 8401139

Cumming, Georgia, 30040, United States
Clinica de Alergia Martti Antila- Site Number : 0760006

Sorocaba, São Paulo, 18040-425, Brazil
Clinical Neuroscience Solutions - Orlando - South Delaney Avenue- Site Number : 8401035

Orlando, Florida, 32806, United States
Clinical Research of Philadelphia- Site Number : 8401193

Philadelphia, Pennsylvania, 19114, United States
Dermatology Treatment and Research Center- Site Number : 8401164

Dallas, Texas, 75230, United States
Direct Helpers Research Center- Site Number : 8401056

Hialeah, Florida, 33012, United States
Encore Medical Research- Site Number : 8401030

Hollywood, Florida, 33021, United States
Faculdade de Medicina do ABC- Site Number : 0760001

Santo André, 09060-650, Brazil
First OC Dermatology- Site Number : 8401025

Fountain Valley, California, 92708, United States
Florida International Research Center- Site Number : 8401091

Miami, Florida, 33173, United States
Henry Ford Hospital- Site Number : 8401044

Detroit, Michigan, 48202, United States
Hospital São Domingos- Site Number : 0760028

Bequimão, Maranhão, 65060-645, Brazil
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo- Site Number : 0760012

São Paulo, 05403-000, Brazil
Hospital de Clinicas da Universidade Federal do Parana- Site Number : 0760022

Curitiba, Paraná, 80060-900, Brazil
Investigational Site Number : 0320010

Buenos Aires, 1414, Argentina
Investigational Site Number : 0320022

Buenos Aires, 1012, Argentina
Investigational Site Number : 0320023

Buenos Aires, Buenos Aires F.D., 1028, Argentina
Investigational Site Number : 0320024

SAN Miguel de Tucumã¡n, Tucumán Province, T4000, Argentina
Investigational Site Number : 0360006

Melbourne, Victoria, 3004, Australia
Investigational Site Number : 0360007

Woolloongabba, Queensland, 4102, Australia
Investigational Site Number : 0360008

Melbourne, Victoria, 3002, Australia
Investigational Site Number : 0360010

Westmead, New South Wales, 2145, Australia
Investigational Site Number : 0361006

Traralgon, Victoria, 3844, Australia
Investigational Site Number : 1240013

Toronto, Ontario, M3B 3N1, Canada
Investigational Site Number : 1240028

Regina, Saskatchewan, S4V 1R9, Canada
Investigational Site Number : 1240029

London, Ontario, N6A 2C2, Canada
Investigational Site Number : 1240031

Edmonton, Alberta, T5K 2V4, Canada
Investigational Site Number : 1240033

Ajax, Ontario, L1S 7K8, Canada
Investigational Site Number : 1240034

Ottawa, Ontario, K1H 7X8, Canada
Investigational Site Number : 1240035

Toronto, Ontario, M5A 3R6, Canada
Investigational Site Number : 1240036

Saskatoon, Saskatchewan, S7K 0H6, Canada
Investigational Site Number : 1240040

Surrey, British Columbia, V3R 6A7, Canada
Investigational Site Number : 1240043

Saint-Jérôme, Quebec, J7Z 7E2, Canada
Investigational Site Number : 1240055

Hamilton, Ontario, L8S 1G5, Canada
Investigational Site Number : 1241108

Niagara Falls, Ontario, L2H 1H5, Canada
Investigational Site Number : 1520001

Santiago, Reg Metropolitana de Santiago, 8420383, Chile
Investigational Site Number : 1520002

Santiago, Reg Metropolitana de Santiago, 7580206, Chile
Investigational Site Number : 1520003

Santiago, Reg Metropolitana de Santiago, 7640881, Chile
Investigational Site Number : 1520005

Santiago, Reg Metropolitana de Santiago, 8380465, Chile
Investigational Site Number : 1520006

Viña del Mar, Región de Valparaíso, 2530900, Chile
Investigational Site Number : 1520008

Santiago, Reg Metropolitana de Santiago, 7500587, Chile
Investigational Site Number : 1520009

Osorno, Reg Metropolitana de Santiago, 5311523, Chile
Investigational Site Number : 1520010

Santiago, Reg Metropolitana de Santiago, 8330034, Chile
Investigational Site Number : 1520011

Santiago, Reg Metropolitana de Santiago, 8380456, Chile
Investigational Site Number : 1520012

Talcahuano, 2687000, Chile
Investigational Site Number : 1560042

Beijing, 100034, China
Investigational Site Number : 1560057

Chongqing, 400016, China
Investigational Site Number : 1560058

Guangzhou, 510630, China
Investigational Site Number : 1560059

Jinan, 250014, China
Investigational Site Number : 1560060

Chengdu, 610072, China
Investigational Site Number : 1560064

Shenzhen, 518026, China
Investigational Site Number : 1560065

Chongqing, 400065, China
Investigational Site Number : 1560068

Chengdu, 610091, China
Investigational Site Number : 1580001

Taipei, 100, Taiwan
Investigational Site Number : 1580003

Taipei, Taiwan
Investigational Site Number : 1583201

Kaohsiung City, 833, Taiwan
Investigational Site Number : 1583202

Taichung, 402, Taiwan
Investigational Site Number : 1583203

Taoyuan, 333, Taiwan
Investigational Site Number : 2500003

Paris, 75010, France
Investigational Site Number : 2500007

Reims, 51100, France
Investigational Site Number : 2500008

Antony, 92160, France
Investigational Site Number : 2500009

Nantes, 44093, France
Investigational Site Number : 2500010

Romans-sur-Isère, 26102, France
Investigational Site Number : 2760009

Bad Bentheim, 48455, Germany
Investigational Site Number : 2760014

Buxtehude, 21614, Germany
Investigational Site Number : 2760016

Mainz, 55128, Germany
Investigational Site Number : 2760017

Hamburg, 20095, Germany
Investigational Site Number : 2760018

Magdeburg, 39104, Germany
Investigational Site Number : 2762201

Münster, 48149, Germany
Investigational Site Number : 2762208

Kiel, 24105, Germany
Investigational Site Number : 3000001

Athens, 161 21, Greece
Investigational Site Number : 3000002

Thessaloniki, 546 42, Greece
Investigational Site Number : 3000003

Thessaloniki, 564 29, Greece
Investigational Site Number : 3000004

Athens, 124 62, Greece
Investigational Site Number : 3560001

Ahmedabad, 380016, India
Investigational Site Number : 3560002

Nagpur, 440015, India
Investigational Site Number : 3560003

Pune, 411057, India
Investigational Site Number : 3560004

Chandigarh, 160012, India
Investigational Site Number : 3560005

Belagavi, 590002, India
Investigational Site Number : 3560006

Haryāna, 121002, India
Investigational Site Number : 3560007

Kolkata, 700073, India
Investigational Site Number : 3560008

Bengaluru, 560090, India
Investigational Site Number : 3760001

Haifa, 3109601, Israel
Investigational Site Number : 3760002

Petah Tikva, 4941492, Israel
Investigational Site Number : 3760003

Jerusalem, 9112001, Israel
Investigational Site Number : 3760004

Afula, 1834111, Israel
Investigational Site Number : 3760005

Beersheba, 8457108, Israel
Investigational Site Number : 3760006

Petah Tikva, 4920235, Israel
Investigational Site Number : 4100002

Ansan-si, Gyeonggi-do, 15355, South Korea
Investigational Site Number : 4100003

Yangsan, Gyeongsangnam-do, 50612, South Korea
Investigational Site Number : 4100006

Seoul, Seoul-teukbyeolsi, 05030, South Korea
Investigational Site Number : 4100007

Seoul, Seoul-teukbyeolsi, 03722, South Korea
Investigational Site Number : 4100008

Daegu, Daegu, 41944, South Korea
Investigational Site Number : 4100009

Suwon, Gyeonggi-do, 16499, South Korea
Investigational Site Number : 4100010

Seoul, Seoul-teukbyeolsi, 01812, South Korea
Investigational Site Number : 4100011

Seoul, Seoul-teukbyeolsi, 06591, South Korea
Investigational Site Number : 4100012

Gwangju, 61453, South Korea
Investigational Site Number : 4100013

Seoul, Seoul-teukbyeolsi, 03080, South Korea
Investigational Site Number : 4100014

Seongnam-si, Gyeonggi-do, 13620, South Korea
Investigational Site Number : 4100015

Bupyeong-gu, Incheon-gwangyeoksi, 21431, South Korea
Investigational Site Number : 4100017

Seoul, Seoul-teukbyeolsi, 07804, South Korea
Investigational Site Number : 6160002

Lodz, 90-265, Poland
Investigational Site Number : 6160003

Katowice, Silesian Voivodeship, 40-611, Poland
Investigational Site Number : 6160004

Lublin, 20-607, Poland
Investigational Site Number : 6160006

Gdansk, Pomeranian Voivodeship, 80-546, Poland
Investigational Site Number : 6160007

Warsaw, 02-962, Poland
Investigational Site Number : 6160009

Warsaw, 02-625, Poland
Investigational Site Number : 6160010

Tarnów, 33-100, Poland
Investigational Site Number : 6160011

Olsztyn, 11-041, Poland
Investigational Site Number : 6162406

Krakow, 31-209, Poland
Irmandade da Santa Casa de Misericórdia de Porto Alegre- Site Number : 0760005

Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Javara Research - Thomasville- Site Number : 8401189

Thomasville, Georgia, 31792, United States
Massachusetts General Hospital- Site Number : 8401192

Boston, Massachusetts, 02114, United States
MedPharmics - Covington- Site Number : 8401137

Covington, Louisiana, 70433, United States
MedPharmics - Lafeyette- Site Number : 8401152

Lafayette, Louisiana, 70508, United States
MediSearch Clinical Trials- Site Number : 8401140

Saint Joseph, Missouri, 64506, United States
Metro Boston Clinical Partners- Site Number : 8401128

Needham, Massachusetts, 02492, United States
Miami Dermatology and Laser Research- Site Number : 8401086

Miami, Florida, 33173, United States
Northridge Clinical Trials - Northridge- Site Number : 8401080

Northridge, California, 91325, United States
Onsite Clinical Solutions - Charlotte - Blakeney Park Drive- Site Number : 8401124

Charlotte, North Carolina, 28277, United States
Oregon Medical Research Center- Site Number : 8401017

Portland, Oregon, 97201, United States
PUC Trials- Nucleo de Pesquisa clinica da Escola de Medicina da PUCPR- Site Number : 0760023

Curitiba, Paraná, 80230-130, Brazil
Paddington Testing Company- Site Number : 8401041

Philadelphia, Pennsylvania, 19103, United States
Revival Research - Doral- Site Number : 8401012

Dearborn, Michigan, 33122, United States
Rophe Adult & Pediatric Medicine- Site Number : 8401289

Union City, Georgia, 30291, United States
SKY Integrative Medical Center/SKYCRNG - Ridgeland- Site Number : 8401058

Ridgeland, Mississippi, 39157, United States
Sadick Research Group - New York - Park Avenue- Site Number : 8401050

New York, New York, 10075, United States
Scottsdale Clinical Trials- Site Number : 8401149

Scottsdale, Arizona, 85260, United States
Skin Care Physicians of Georgia - Macon- Site Number : 8401034

Macon, Georgia, 31217, United States
Skin Sciences- Site Number : 8401039

Louisville, Kentucky, 40217, United States
Skin Specialist of Addison- Site Number : 8401208

Dallas, Texas, 75254, United States
Somnos Clinical Research- Site Number : 8401203

Lincoln, Nebraska, 68510, United States
Springville Dermatology - Springville- Site Number : 8401106

Springville, Utah, 84663, United States
St Jude Clinical Research- Site Number : 8401287

Doral, Florida, 33172, United States
Stryde Research - Epiphany Dermatology- Site Number : 8401185

Southlake, Texas, 76092, United States
Sunwise Clinical Research- Site Number : 8401022

Lafayette, California, 94549, United States
Texas Dermatology and Laser Specialists- Site Number : 8401131

San Antonio, Texas, 78218, United States
Tribe Clinical Research - 525 Verdae Boulevard- Site Number : 8401225

Greenville, South Carolina, 29607, United States
Universal Dermatology- Site Number : 8401224

Fairport, New York, 14450, United States
Vial Health - DermDox Dermatology- Site Number : 8401031

Camp Hill, Pennsylvania, 17011, United States
Virginia Dermatology & Skin Cancer Center- Site Number : 8401047

Norfolk, Virginia, 23502, United States

Conditions

Explore the condition pages connected to this study.

DERMATITIS, ATOPIC