New drug combo tested to help frail AML patients live longer
NCT ID NCT02752035
Summary
This study tested whether adding a new drug called gilteritinib to standard azacitidine treatment helps adults with a specific type of acute myeloid leukemia (AML) live longer. It focused on older adults or those with other health problems who could not tolerate strong chemotherapy. Researchers randomly assigned participants to receive either the two-drug combination or azacitidine alone to compare survival and other outcomes.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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GHS Cancer Institute
Greenville, South Carolina, 26615, United States
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Hackensack University Medical Center - John Theurer Cancer Center
Hackensack, New Jersey, 07601, United States
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Hematology-Oncology Associates of Northern NJ
Morristown, New Jersey, 07962, United States
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LDS Hospital
Salt Lake City, Utah, 84143, United States
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10021, United States
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Robert H. Lurie Comprehensive Cancer Center
Chicago, Illinois, 60611-5975, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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Site AU61004
Liverpool, New South Wales, 2170, Australia
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Site AU61007
Geelong, Victoria, 3220, Australia
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Site AU61008
Adelaide, South Australia, SA 5000, Australia
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Site BE32003
Brussels, Bruxelles-Capitale, Region de, 1200, Belgium
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Site BE32006
Ghent, 9000, Belgium
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Site BE32007
Brussels, Brussels Capital, 1090, Belgium
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Site CA15002
Toronto, Ontario, M5G 2M9, Canada
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Site CA15006
Montreal, Quebec, H4A 3J1, Canada
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Site CA15009
Edmonton, Alberta, T6G 2B7, Canada
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Site CA15011
Toronto, Ontario, M4N 3M5, Canada
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Site DE49002
Tübingen, Baden-Wurttemberg, 72076, Germany
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Site DE49003
Berlin, 13353, Germany
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Site DE49004
Hanover, Lower Saxony, 30625, Germany
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Site DE49005
Frankfurt am Main, Hesse, 60590, Germany
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Site DE49007
München, Bavaria, 81737, Germany
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Site DE49009
Halle, Saxony-Anhalt, 06120, Germany
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Site DE49011
Stuttgart, 70376, Germany
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Site DE49012
Braunschweig, Lower Saxony, 38118, Germany
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Site DE49015
Rostock, Mecklenburg-Vorpommern, 18057, Germany
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Site ES34002
Cáceres, 10003, Spain
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Site ES34003
Oviedo, Principality of Asturias, 33011, Spain
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Site ES34004
Barcelona, 08035, Spain
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Site ES34005
Valencia, 46026, Spain
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Site ES34007
Palma de Mallorca, Balearic Islands, 07010, Spain
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Site ES34008
Barcelona, 08003, Spain
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Site ES34009
Barcelona, 8041, Spain
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Site ES34010
Barcelona, 08036, Spain
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Site ES34013
Madrid, Spain
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Site FR33001
Nantes, Loire-Atlantique, 44093, France
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Site FR33002
Pessac, Gironde, 33604, France
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Site FR33003
Nîmes, Gard, 30029, France
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Site FR33004
Lille, 59020, France
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Site FR33006
Lille, 59037, France
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Site FR33009
Angers, 49033, France
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Site FR33012
Poitiers, Vienne, 86000, France
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Site FR33013
Pierre-Bénite, Rhone, 69310, France
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Site FR33015
Rouen, Haute-Normandie, 76038, France
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Site FR33017
Le Mans, Sarthe, 72037, France
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Site FR33018
Rennes, Ille-et-Vilaine, 35033, France
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Site FR33019
Montpellier, Herault, 34295, France
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Site FR33020
Bayonne, France
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Site FR33023
Valenciennes, Nord, 59322, France
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Site GB44007
Sheffield, S10 2JF, United Kingdom
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Site IT39001
Naples, 80131, Italy
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Site IT39004
Milan, 20162, Italy
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Site IT39005
Pavia, Italy
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Site IT39006
Palermo, 90146, Italy
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Site IT39007
Monza, Italy
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Site IT39009
Ancona, 60126, Italy
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Site IT39011
San Giovanni Rotondo, 71013, Italy
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Site IT39012
Florence, Italy
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Site IT39014
Novara, Italy
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Site IT39015
Bologna, 40138, Italy
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Site JP81001
Isehara, Kanagawa, Japan
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Site JP81004
Nagasaki, Japan
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Site JP81005
Kumamoto, Japan
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Site JP81007
Nagoya, Aichi-ken, Japan
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Site JP81008
Fukuoka, Japan
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Site JP81011
Kurashiki, Okayama-ken, Japan
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Site JP81012
Sendai, Miyagi, Japan
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Site JP81014
Shinagawa-ku, Tokyo, Japan
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Site JP81015
Kobe, Hyōgo, Japan
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Site JP81016
Kyoto, Japan
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Site JP81017
Nagasaki, Japan
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Site JP81018
Anjo, Aichi-ken, Japan
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Site JP81019
Toyama, Japan
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Site JP81021
Fukuyama, Hiroshima, Japan
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Site JP81023
Kanazawa, Ishikawa-ken, Japan
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Site JP81024
Gifu, Japan
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Site JP81026
Tokushima, Japan
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Site JP81027
Matsuyama, Ehime, Japan
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Site JP81029
Shibuya-ku, Tokyo, Japan
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Site JP81030
Osaka, Japan
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Site JP81031
Sapporo, Hokkaido, Japan
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Site JP81032
Yokohama, Kanagawa, Japan
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Site JP81033
Sapporo, Hokkaido, Japan
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Site JP81034
Hitachi, Ibaraki, Japan
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Site JP81035
Chiba, Japan
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Site JP81036
Osaka, Japan
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Site KR82001
Ulsan, Ulsan Gwang'yeogsi, 682-714, South Korea
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Site KR82002
Seoul, Seoul Teugbyeolsi, 137-701, South Korea
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Site KR82003
Namdong, Incheon Gwang'yeogsiv, 405 760, South Korea
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Site KR82006
Seoul, Seoul Teugbyeolsi, 110-744, South Korea
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Site KR82010
Hwasun-gun, South Korea
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Site KR82012
Seoul, 156-707, South Korea
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Site KR82013
Seoul, Seoul Teugbyeolsi, 05505, South Korea
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Site KR82014
Busan, 49241, South Korea
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Site KR82015
Seongnam-si, South Korea
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Site PL48001
Olsztyn, Warmian-Masurian Voivodeship, 10-228, Poland
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Site PL48002
Opole, Opole Voivodeship, 45-061, Poland
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Site PL48003
Lublin, Lublin Voivodeship, 20-081, Poland
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Site PL48004
Warsaw, Masovian Voivodeship, 02-776, Poland
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Site TW88601
Taipei, 10002, Taiwan
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Site TW88602
Tainan, 704, Taiwan
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Site TW88604
Kaohsiung City, 83301, Taiwan
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Site TW88605
Kwei Shan Hsiang, Taiwan
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Site TW88608
Taipei, 10449, Taiwan
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Site TW88609
Tainan, 736, Taiwan
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Site TW88610
Taipei, 11217, Taiwan
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St. Louis University Cancer Center - Hematology/Oncology
St Louis, Missouri, 63110, United States
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UCLA David Geffen School of Medicine
Los Angeles, California, 90095, United States
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University of California, Irvine Medical Center
Orange, California, 92868, United States
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Weill Cornell Medical College-New York Presbyterian Hospital
New York, New York, 10021, United States
Conditions
Explore the condition pages connected to this study.