New hope for aggressive blood cancer: adding a targeted drug to standard chemo

NCT ID NCT02310321

Summary

This study tested whether adding a new targeted drug called gilteritinib to standard chemotherapy was safe and effective for people newly diagnosed with acute myeloid leukemia (AML), a fast-growing blood cancer. The first part of the study aimed to find the safest dose. The second part focused on patients with a specific genetic change (FLT3 mutation) to see if the combination helped them achieve remission. The goal was to better control the disease.

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Contacts and locations

Locations

  • SIte JP81011

    Ōmura, Nagasaki, Japan

  • Site JP00001

    Fukuoka, Japan

  • Site JP00002

    Maebashi, Gunma, Japan

  • Site JP00003

    Nagoya, Aichi-ken, Japan

  • Site JP00005

    Shinagawa-ku, Tokyo, Japan

  • Site JP00006

    Yokohama, Kanagawa, Japan

  • Site JP00007

    Kobe, Hyōgo, Japan

  • Site JP81001

    Maebashi, Gunma, Japan

  • Site JP81003

    Nagoya, Aichi-ken, Japan

  • Site JP81004

    Fukuoka, Japan

  • Site JP81005

    Yokohama, Kanagawa, Japan

  • Site JP81006

    Kobe, Hyōgo, Japan

  • Site JP81007

    Yoshida-gun, Fukui, Japan

  • Site JP81008

    Chiba, Japan

  • Site JP81009

    Okayama, Japan

  • Site JP81010

    Narita, Chiba, Japan

  • Site JP81012

    Nagasaki, Japan

  • Site JP81013

    Isehara, Kanagawa, Japan

  • Site JP81014

    Sapporo, Hokkaido, Japan

  • Site JP81015

    Sapporo, Hokkaido, Japan

  • Site JP81016

    Kyoto, Japan

  • Site JP81018

    Ōtake, Hiroshima, Japan

  • Site JP81019

    Osaka, Japan

  • Site JP81020

    Kanazawa, Ishikawa-ken, Japan

  • Site JP81021

    Osaka, Japan

  • Site JP81022

    Shimono, Tochigi, Japan

  • Site JP81023

    Tsukuba, Ibaraki, Japan

  • Site JP81024

    Yokohama, Kanagawa, Japan

  • Site JP81025

    Fukuoka, Japan

  • Site JP81026

    Fukuyama, Hiroshima, Japan

  • Site JP81027

    Nagoya, Aichi-ken, Japan

  • Site JP81028

    Kumamoto, Japan

  • Site JP81029

    Akita, Japan

  • Site JP81030

    Gifu, Japan

  • Site JP81031

    Fukushima, Japan

  • Site JP81032

    Shinagawa-ku, Tokyo, Japan

  • Site JP81033

    Kochi, Japan

  • Site JP81035

    Sendai, Miyagi, Japan

  • Site JP81036

    Mito, Ibaraki, Japan

  • Site JP81037

    Anjo, Aichi-ken, Japan

  • Site JP81038

    Toyohashi, Aichi-ken, Japan

  • Site JP81039

    Matsuyama, Ehime, Japan

  • Site JP81040

    Bunkyo-ku, Tokyo, Japan

  • Site JP81041

    Tenri, Nara, Japan

  • Site JP81043

    Himeji, Hyōgo, Japan

  • Site KR82001

    Seoul, South Korea

  • Site KR82002

    Incheon, South Korea

  • Site KR82003

    Seoul, South Korea

  • Site KR82004

    Seoul, South Korea

  • Site KR82005

    Busan, South Korea

  • Site KR82006

    Seoul, South Korea

  • Site TW88601

    Tainan, Taiwan

  • Site TW88602

    Taichung, Taiwan

  • Site TW88603

    Taoyuan District, Taiwan

  • Site TW88604

    Kaohsiung City, Taiwan

Conditions

Explore the condition pages connected to this study.