Targeted attack on blood cancer offers hope for frail patients
NCT ID NCT02677922
Summary
This study is testing two new drug combinations for adults newly diagnosed with a specific genetic type of acute myeloid leukemia (AML) who are not healthy enough for standard intensive chemotherapy. The goal is to find safe and effective doses and see if adding a new targeted pill to a standard drug works better than the standard drug alone. It is for patients whose cancer has a specific genetic change called an IDH1 or IDH2 mutation.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02115, United States
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Local Institution - 102
Boston, Massachusetts, 02114, United States
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Local Institution - 103
Chicago, Illinois, 60637, United States
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Local Institution - 105
Duarte, California, 91010-301, United States
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Local Institution - 106
New York, New York, 10065, United States
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Local Institution - 107
New Haven, Connecticut, 06510, United States
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Local Institution - 108
Chicago, Illinois, 60611, United States
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Local Institution - 110
Dallas, Texas, 75390-85520, United States
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Local Institution - 125
Toronto, Ontario, M5G 2M9, Canada
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Local Institution - 175
Melbourne, 3141, Australia
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Local Institution - 177
Perth, 6000, Australia
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Local Institution - 178
Adelaide, South Australia, SA 5000, Australia
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Local Institution - 200
Paris, 75475, France
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Local Institution - 201
Villejuif, 94805, France
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Local Institution - 202
Pierre-Bénite, 69495, France
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Local Institution - 203
Toulouse, 31059, France
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Local Institution - 204
Pessac, 33604, France
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Local Institution - 205
Lille, 59037, France
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Local Institution - 206
Marseille, 13273, France
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Local Institution - 225
Ulm, 89081, Germany
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Local Institution - 227
Berlin, 12200, Germany
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Local Institution - 230
Dresden, 01307, Germany
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Local Institution - 250
Pesaro, 31122, Italy
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Local Institution - 251
Orbassano, 10043, Italy
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Local Institution - 252
Florence, 50134, Italy
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Local Institution - 253
Bologna, Emilia-Romagna, 40138, Italy
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Local Institution - 254
Padua, 35128, Italy
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Local Institution - 255
Roma, 00189, Italy
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Local Institution - 256
Genova, 16132, Italy
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Local Institution - 277
Utrecht, 3584 CX, Netherlands
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Local Institution - 327
Lisbon, 1169-050, Portugal
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Local Institution - 350
Seoul, 138-736, South Korea
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Local Institution - 351
Seoul, 135-710, South Korea
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Local Institution - 375
Barcelona, 08907, Spain
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Local Institution - 376
Cáceres, 10005, Spain
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Local Institution - 377
Valencia, 46009, Spain
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Local Institution - 378
Madrid, 28007, Spain
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Local Institution - 379
Barcelona, 08036, Spain
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Local Institution - 380
Málaga, 29010, Spain
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Local Institution - 381
Madrid, 28033, Spain
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Local Institution - 401
Zurich, 0, Switzerland
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Local Institution - 403
Basel, 4031, Switzerland
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Local Institution - 427
Headington, OX3 9DU, United Kingdom
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Local Institution - 428
London, SE5 9RS, United Kingdom
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Local Institution - 429
Birmingham, B15 2TH, United Kingdom
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Local Institution - 430
Sutton (Surrey), SM2 5PT, United Kingdom
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Local Institution - 902
Boston, Massachusetts, 02115, United States
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Local Institution - UNK-121
Yvoir, 5530, Belgium
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Local Institution - UNK-52
Gothenburg, 413 45, Sweden
Conditions
Explore the condition pages connected to this study.