New drug cocktail tested for Tough-to-Treat leukemia in frail patients

NCT ID NCT04964505

Summary

This early-stage study tested the safety of combining three drugs—uproleselan, azacitidine, and venetoclax—for older adults or those too frail for standard intensive chemotherapy who have newly diagnosed acute myeloid leukemia (AML). The goal was to find a safe dose and see if this combination could effectively kill cancer cells. The study was small and terminated early, focusing primarily on side effects and dosing.

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Contacts and locations

Locations

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

Conditions

Explore the condition pages connected to this study.