Fighting leukemia relapse with Donor's supercharged immune cells

NCT ID NCT04511130

Summary

This study tested whether specially prepared immune cells from a stem cell donor could help patients with acute myeloid leukemia (AML) after their transplant. The cells, called MT-401, were given to try to prevent the cancer from coming back or to treat it if it did return. The trial involved 92 adults and aimed to measure safety and how well the treatment worked, but it was stopped early.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Cleveland Clinic Taussig Cancer Center

    Cleveland, Ohio, 44195, United States

  • John Theurer Cancer Center at Hackensack UMC

    Hackensack, New Jersey, 07601, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic Cancer Center-Rochester

    Rochester, Minnesota, 55905, United States

  • Mayo Clinical Cancer Center-Florida

    Jacksonville, Florida, 32224, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Moores Cancer Center at University of Californa San Diego

    La Jolla, California, 92093, United States

  • UCLA Department of Medicine

    Los Angeles, California, 90095, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35249, United States

  • University of Chicago

    Chicago, Illinois, 77027, United States

  • University of Iowa Hospitals & Clinics

    Iowa City, Iowa, 52242, United States

  • Weill Cornell Medicine | NewYork-Presbyterian

    New York, New York, 10027, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, 303222, United States

  • Yale Cancer Center

    New Haven, Connecticut, 06519, United States

Conditions

Explore the condition pages connected to this study.