New heart valve fix could spare patients from open surgery

NCT ID NCT06951672

First seen Jan 07, 2026 · Last updated May 06, 2026 · Updated 22 times

Summary

This early study tests a new device called the AMEND Trans-Septal system, which is placed through a tube in a blood vessel to repair a leaky mitral valve without open-heart surgery. Up to 15 people with moderate-to-severe mitral regurgitation will be enrolled to see if the device is safe and works as intended. The main goal is to check for serious complications within 30 days after the procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ascension St. Vincent

    RECRUITING

    Indianapolis, Indiana, 46260, United States

    Contact

    Contact Email: •••••@•••••

  • Banner University Medical Center - Phoenix

    RECRUITING

    Phoenix, Arizona, 85006, United States

    Contact Email: •••••@•••••

    Contact

  • Columbia University Medical Center (CUMC)

    RECRUITING

    New York, New York, 10032, United States

    Contact Email: •••••@•••••

    Contact

  • Intermountain Health

    NOT_YET_RECRUITING

    Murray, Utah, 84107, United States

    Contact

    Contact Email: •••••@•••••

  • Methodist Hospital HCA

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Email: •••••@•••••

    Contact

  • Montefiore Medical Center

    NOT_YET_RECRUITING

    The Bronx, New York, 10467, United States

    Contact

    Contact Email: •••••@•••••

  • Oregon Health & Science University (OHSU)

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Email: •••••@•••••

    Contact

  • Piedmont Healthcare

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30309, United States

    Contact Email: •••••@•••••

    Contact

  • Saint Thomas Research Institute

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37205, United States

    Contact Email: •••••@•••••

    Contact

  • Scripps Health

    NOT_YET_RECRUITING

    La Jolla, California, 92037, United States

    Contact Email: •••••@•••••

    Contact

  • University of Texas Health Science Center (UTH)

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.